Speiser P
Wien Med Wochenschr. 1986 Feb 15;136(3):53-6.
The chance of paternity exclusion shows 99.99% using 26 hemogenetic marker systems. Furthermore mixed lymphocyte culture-test (MLC) is able to exclude the falsely accused man in certain mother-child pairs. The lymphocyte culture of the child with his father's MLC haplotype can stimulate the maternal lymphocytes. The "primed" mother reacts in a second stimulation with the child's-father cells very strongly and in a short time of cultivation, but gives no reaction, when cultured with "non father" cells, lacking the paternal haplotype. All possible parents-sibling-combinations are noted and samples of positive and negative results in disputed paternity cases are demonstrated on basis of this new conception.
使用26个血液遗传标记系统时,排除父系的概率显示为99.99%。此外,混合淋巴细胞培养试验(MLC)能够在某些母婴对中排除被错误指控的男子。孩子与父亲的MLC单倍型的淋巴细胞培养可以刺激母亲的淋巴细胞。“致敏”的母亲在第二次刺激时与孩子父亲的细胞反应非常强烈,且培养时间短,但与缺乏父系单倍型的“非父亲”细胞培养时则无反应。记录所有可能的父母-兄弟姐妹组合,并基于这一新概念展示有争议亲子鉴定案例中的阳性和阴性结果样本。