Huber H P, Nook T
Z Hautkr. 1986 Mar 1;61(5):320-2.
The efficacy of Clotrimazol cream paste containing a penetration enhancer in the treatment of acne vulgaris was objectified by investigating the sebum composition. Following treatment over three and six weeks, the ratio of triglyceride to free fatty acid significantly increased, which indicated an effective reduction of the lipase activity of Propionibacterium acnes within the sebaceous follicle.
通过研究皮脂成分来客观评估含渗透促进剂的克霉唑乳膏糊剂治疗寻常痤疮的疗效。经过三周和六周的治疗后，甘油三酯与游离脂肪酸的比例显著增加，这表明皮脂腺毛囊内痤疮丙酸杆菌的脂肪酶活性有效降低。
