Department of Respiratory Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
J Zhejiang Univ Sci B. 2011 Apr;12(4):298-302. doi: 10.1631/jzus.B1000261.
Coccidioidomycosis is an endemic disease of the Western hemisphere. The cases in non-endemic areas are mostly imported. Determining a history of exposure is critical for performing the diagnosis of coccidioidomycosis, especially for cases occurring in a non-endemic area. In this study, a 71-year-old Chinese male presented to our hospital with chronic cough and malaise, and was found to have a mass in the middle lobe of right lung. He had been visiting Arizona, USA for four months before admission. Pulmonary coccidioidomycosis was confirmed by the results of histopathological examination after lobectomy. Typical microscopic features of Coccidioides are definitely diagnostic, but need be differentiated from other budding yeast infection or carcinoma histopathologically.
球孢子菌病是西半球的一种地方病。非流行地区的病例大多为输入性。确定接触史对于球孢子菌病的诊断至关重要,特别是对于非流行地区发生的病例。在本研究中,一名71岁的中国男性因慢性咳嗽和不适前来我院就诊,发现右肺中叶有一肿块。入院前他在美国亚利桑那州访问了四个月。肺叶切除术后组织病理学检查结果证实为肺球孢子菌病。球孢子菌的典型微观特征具有明确的诊断意义,但在组织病理学上需要与其他芽生酵母菌感染或癌进行鉴别。