菊粉与含多酚的红小豆提取物组合对体外和体内肠道发酵的影响。
Effect of a combination of inulin and polyphenol-containing adzuki bean extract on intestinal fermentation in vitro and in vivo.
作者信息
Nagata Ryuji, Echizen Mao, Yamaguchi Yukari, Han Kyu-Ho, Shimada Kenichiro, Ohba Kiyoshi, Kitano-Okada Tomoko, Nagura Taizo, Uchino Hirokatsu, Fukushima Michihiro
机构信息
a Department of Life and Food Sciences , Obihiro University of Agriculture and Veterinary Medicine , Obihiro , Japan.
b The United Graduate School of Agricultural Sciences , Iwate University , Morioka , Japan.
出版信息
Biosci Biotechnol Biochem. 2018 Mar;82(3):489-496. doi: 10.1080/09168451.2018.1429886. Epub 2018 Jan 31.
The effect of a combination of inulin (INU) and polyphenol-containing adzuki bean extract (AE) on intestinal fermentation was examined in vitro using fermenters for 48 h and in vivo using rats for 28 d. The total short-chain fatty acid concentrations in the fermenters were decreased by a combination of INU and AE, but the concentration in the INU + AE group was higher than the cellulose (CEL) and CEL + AE groups. The cecal propionate concentration was increased by a combination of INU and AE compared with their single supplement. The ammonia-nitrogen concentration in the fermenters and rat cecum was decreased by INU and AE. Cecal mucin levels were increased by INU and AE respectively. Therefore, our observations suggested that the combination of INU and AE might be a material of functional food that includes several healthy effects through intestinal fermentation.
使用发酵罐在体外进行48小时以及在体内使用大鼠进行28天的实验，研究了菊粉（INU）和含多酚的赤小豆提取物（AE）组合对肠道发酵的影响。发酵罐中的总短链脂肪酸浓度因INU和AE的组合而降低，但INU + AE组的浓度高于纤维素（CEL）和CEL + AE组。与单独补充相比，INU和AE的组合使盲肠丙酸浓度增加。INU和AE降低了发酵罐和大鼠盲肠中的氨氮浓度。INU和AE分别提高了盲肠粘蛋白水平。因此，我们的观察结果表明，INU和AE的组合可能是一种功能性食品原料，通过肠道发酵具有多种健康益处。
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