Department of Life and Food Sciences, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.
Food Funct. 2020 Nov 18;11(11):10182-10192. doi: 10.1039/d0fo02111c.
A polyphenol-rich diet has been associated with various health benefits. This study assessed the effects of polyphenol/anthocyanin isolated from a purple sweet potato (Ipomoea batatas cv. Ayamurasaki) on colonic fermentation in cellulose- or inulin-fed rats. Male Fischer-344 rats were assigned to one of these experimental diets: 5% cellulose (CEL), 5% CEL + 1% purple sweet potato polyphenol extract (CELP), 5% inulin (INU), and 5% INU + 1% purple sweet potato polyphenol extract (INUP) in each diet. The purple sweet potato polyphenol extract (PSPP) increased the relative abundance of Dorea and reduced the relative abundances of Oscillospira and Bacteroides in cellulose- or inulin-fed rats, respectively. Besides, PSPP reduced the caecal iso-butyrate and pH in the cellulose-fed rats. Further, PSPP triggered an increase in the caecal mucin level when combined with cellulose and increased the caecal IgA level while reducing the indole production in both the cellulose- or inulin-fed rats. Finally, PSPP may have different effects on the intestinal fermentation properties depending on the fermentability of dietary fiber associated with it. Therefore, this study demonstrated that dietary inclusion of polyphenol/anthocyanin from purple sweet potato might confer positive health attributes to the host gut.
富含多酚的饮食与多种健康益处有关。本研究评估了从紫色甘薯（Ipomoea batatas cv. Ayamurasaki）中分离的多酚/花青素对纤维素或菊粉喂养大鼠结肠发酵的影响。雄性 Fischer-344 大鼠被分配到以下实验饮食中的一种：5%纤维素（CEL）、5%CEL+1%紫色甘薯多酚提取物（CELP）、5%菊粉（INU）和 5%INU+1%紫色甘薯多酚提取物（INUP）。紫色甘薯多酚提取物（PSPP）增加了 Dorea 的相对丰度，降低了纤维素或菊粉喂养大鼠中 Oscillospira 和 Bacteroides 的相对丰度。此外，PSPP 降低了纤维素喂养大鼠的盲肠异丁酸和 pH 值。此外，PSPP 与纤维素结合可增加盲肠粘蛋白水平，并增加纤维素或菊粉喂养大鼠的盲肠 IgA 水平，同时降低吲哚的产生。最后，PSPP 可能对与膳食纤维可发酵性相关的肠道发酵特性有不同的影响。因此，本研究表明，紫色甘薯中多酚/花青素的膳食摄入可能为宿主肠道带来积极的健康属性。
