关于“基于修订的CIMP分类系统的两种CIMP阳性结直肠癌亚型的不同临床结局”的评论 - Suppr

Comment on 'Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification system'.

作者信息

Tapial Sandra, Rueda Daniel, Arriba María, Luis García Juan, Brandáriz Lorena, Pérez Jessica, Rodríguez Yolanda, García-Olmo Damián, González-Sarmiento Rogelio, Urioste Miguel, Perea José

机构信息

Digestive Cancer Research Group, 12 de Octubre Research Institute, Madrid 28041, Spain.

Molecular Biology Laboratory, Department of Biochemistry, 12 de Octubre University Hospital, Madrid 28041, Spain.

出版信息

Br J Cancer. 2018 Feb 6;118(3):e3. doi: 10.1038/bjc.2017.343. Epub 2018 Jan 2.

DOI:10.1038/bjc.2017.343

PMID:29384528

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5808020/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6852/5808020/80f0e3b25678/bjc2017343f1.jpg

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Comment on 'Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification system'.关于“基于修订的CIMP分类系统的两种CIMP阳性结直肠癌亚型的不同临床结局”的评论

Br J Cancer. 2018 Feb 6;118(3):e3. doi: 10.1038/bjc.2017.343. Epub 2018 Jan 2.

Reply to 'Comment on 'Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification system".对《基于修订的CIMP分类系统的两种CIMP阳性结直肠癌亚型的不同临床结局》一文评论的回复

Br J Cancer. 2018 Feb 6;118(3):e4. doi: 10.1038/bjc.2017.426. Epub 2018 Jan 2.

Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification system.基于修订后的CIMP分类系统的两种CIMP阳性结直肠癌亚型的不同临床结局

Br J Cancer. 2017 Apr 11;116(8):1012-1020. doi: 10.1038/bjc.2017.52. Epub 2017 Mar 9.

Colorectal cancer molecular classification using BRAF, KRAS, microsatellite instability and CIMP status: Prognostic implications and response to chemotherapy.结直肠癌的分子分类：BRAF、KRAS、微卫星不稳定性和 CIMP 状态：预后意义和对化疗的反应。

PLoS One. 2018 Sep 6;13(9):e0203051. doi: 10.1371/journal.pone.0203051. eCollection 2018.

Genetic and epigenetic classifications define clinical phenotypes and determine patient outcomes in colorectal cancer.基因和表观遗传分类定义了临床表型，并决定了结直肠癌患者的预后。

Br J Surg. 2009 Oct;96(10):1196-204. doi: 10.1002/bjs.6683.

Age at onset should be a major criterion for subclassification of colorectal cancer.发病年龄应为结直肠癌亚分类的主要标准。

J Mol Diagn. 2014 Jan;16(1):116-26. doi: 10.1016/j.jmoldx.2013.07.010. Epub 2013 Oct 30.

Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype.异柠檬酸脱氢酶1 R132C突变仅发生于具有CpG岛甲基化表型的微卫星稳定型结直肠癌中。

Epigenetics. 2014 Nov;9(11):1454-60. doi: 10.4161/15592294.2014.971624.

Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer.在结直肠癌中，p21（CDKN1A/CIP1）的下调与微卫星不稳定性及CpG岛甲基化表型（CIMP）呈负相关。

J Pathol. 2006 Oct;210(2):147-54. doi: 10.1002/path.2030.

Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.与MGMT启动子甲基化和沉默相关的分子支持结直肠癌中的低CpG岛甲基化表型（CIMP-low）。

Gut. 2007 Nov;56(11):1564-71. doi: 10.1136/gut.2007.119750. Epub 2007 Mar 5.

Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator phenotype.p27（细胞周期蛋白依赖性激酶抑制剂1B/KIP1）在结直肠癌中的细胞质定位：与细胞核p27缺失、微卫星不稳定性及CpG岛甲基化表型呈负相关。

Hum Pathol. 2007 Apr;38(4):585-92. doi: 10.1016/j.humpath.2006.09.014. Epub 2007 Jan 19.

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Br J Cancer. 2018 Feb 6;118(3):e4. doi: 10.1038/bjc.2017.426. Epub 2018 Jan 2.

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Association between mutations of critical pathway genes and survival outcomes according to the tumor location in colorectal cancer.结直肠癌中根据肿瘤位置的关键通路基因突变与生存结局的关系。

Cancer. 2017 Sep 15;123(18):3513-3523. doi: 10.1002/cncr.30760. Epub 2017 May 17.

Br J Cancer. 2017 Apr 11;116(8):1012-1020. doi: 10.1038/bjc.2017.52. Epub 2017 Mar 9.

Toward a Molecular Classification of Synchronous Colorectal Cancer: Clinical and Molecular Characterization.迈向同步性结直肠癌的分子分类：临床与分子特征

Clin Colorectal Cancer. 2017 Mar;16(1):31-37. doi: 10.1016/j.clcc.2016.07.014. Epub 2016 Aug 9.

Multiple primary colorectal cancer: Individual or familial predisposition?多发性原发性结直肠癌：个体易感性还是家族易感性？

World J Gastrointest Oncol. 2015 Dec 15;7(12):434-44. doi: 10.4251/wjgo.v7.i12.434.

Sporadic early-onset colorectal cancer is a specific sub-type of cancer: a morphological, molecular and genetics study.散发性早发性结直肠癌是一种特定的癌症亚型：形态学、分子学和遗传学研究。

PLoS One. 2014 Aug 1;9(8):e103159. doi: 10.1371/journal.pone.0103159. eCollection 2014.

Synchronous colorectal cancer: clinical, pathological and molecular implications.同步性结直肠癌：临床、病理及分子学意义

World J Gastroenterol. 2014 Jun 14;20(22):6815-20. doi: 10.3748/wjg.v20.i22.6815.

Age at onset should be a major criterion for subclassification of colorectal cancer.发病年龄应为结直肠癌亚分类的主要标准。

J Mol Diagn. 2014 Jan;16(1):116-26. doi: 10.1016/j.jmoldx.2013.07.010. Epub 2013 Oct 30.

CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.结肠癌中的CpG岛甲基化表型、微卫星不稳定性、BRAF突变与临床结局

Gut. 2009 Jan;58(1):90-6. doi: 10.1136/gut.2008.155473. Epub 2008 Oct 2.

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