玻璃体内注射贝伐单抗联合光动力疗法治疗脉络膜痣相关的息肉样脉络膜血管病变：一例报告。
Intravitreal bevacizumab associated with photodynamic therapy in a case of polypoidal choroidal vasculopathy associated with choroidal nevus: A case report.
作者信息
Rangel Carlos M, Villota Eva, Fernández-Vega González Álvaro, Sanchez-Avila Ronald M
机构信息
Instituto Universitario Fernández-Vega, Fundación de Investigación Oftalmológica, Oviedo, Spain Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, Colombia.
出版信息
Medicine (Baltimore). 2017 Dec;96(52):e9400. doi: 10.1097/MD.0000000000009400.
RATIONALE
Report the clinical findings and management of a case of polypoidal choroidal vasculopathy associated with choroidal nevus which received combination therapy.
PATIENT CONCERNS
Decreased visual acuity in a woman with polypoidal choroidal vasculopathy and choroidal nevus.
DIAGNOSES
Polypoidal choroidal vasculopathy and choroidal nevus.
INTERVENTIONS
The initial visual acuity was 0.5. After the first treatment with photodynamic therapy, exudation and bleeding appeared around the lesion. After this, the patient received 3 doses of intravitreal bevacizumab.
OUTCOMES
After treatment with combination therapy, visual acuity, clinical and imaging findings improved, with no recurrence of exudation and bleeding.
LESSONS
Intravitreal bevacizumab as an adjunctive treatment after photodynamic therapy is a good option for patients with polypoidal choroidal vasculopathy associated with choroidal nevus.
原理
报告一例接受联合治疗的息肉样脉络膜血管病变合并脉络膜痣的临床发现及治疗情况。
患者情况
一名患有息肉样脉络膜血管病变和脉络膜痣的女性视力下降。
诊断
息肉样脉络膜血管病变和脉络膜痣。
干预措施
初始视力为0.5。首次光动力治疗后，病变周围出现渗出和出血。此后，患者接受了3次玻璃体内注射贝伐单抗。
结果
联合治疗后，视力、临床及影像学表现均有改善，渗出和出血未复发。
经验教训
对于息肉样脉络膜血管病变合并脉络膜痣的患者，玻璃体内注射贝伐单抗作为光动力治疗后的辅助治疗是一个不错的选择。
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