光动力疗法治疗一例合并脉络膜痣的息肉样脉络膜血管病变
Photodynamic therapy in a case of polypoidal choroidal vasculopathy associated with choroidal nevus.
作者信息
Romeo Giuseppe F, Cirone Marinella, Prantera Marcello L
机构信息
From the Department of Ophthalmology, Ospedale Fogliani, Milazzo, Messina, Italy.
出版信息
Retin Cases Brief Rep. 2010 Fall;4(4):381-4. doi: 10.1097/ICB.0b013e3181c6548a.
PURPOSE
The purpose of this study was to report the clinical findings and management of a case of polypoidal choroidal vasculopathy associated with choroidal nevus.
METHODS
A 59-year-old woman with a subfoveal vascular network with polypoidal lesions associated with choroidal nevus was treated with photodynamic therapy. The initial visual acuity was 1/60. Treatment was performed according to identical parameters to those used for choroidal neovascularization secondary to age-related macular degeneration and was repeated 3 months after the first application. The patient was prospectively followed with optical coherence tomography, fluorescein angiography, and indocyanine angiography.
RESULTS
After the second treatment, total occlusion of the polypoidal lesions was observed but the vascular network remained still patent. During the 5-year follow-up, no recurrence was observed and the visual acuity rose to 1/10.
CONCLUSION
In our experience, photodynamic therapy had positive results and this indicates the possibility that it could be a useful tool to manage these lesions and to improve their prognosis.
目的
本研究旨在报告一例与脉络膜痣相关的息肉样脉络膜血管病变的临床发现及治疗情况。
方法
一名59岁女性，其黄斑中心凹下存在伴有息肉样病变的血管网络且与脉络膜痣相关，接受了光动力疗法治疗。初始视力为1/60。治疗采用与年龄相关性黄斑变性继发脉络膜新生血管化相同的参数进行，并在首次治疗3个月后重复进行。对该患者进行了前瞻性光学相干断层扫描、荧光素血管造影和吲哚菁绿血管造影随访。
结果
第二次治疗后，观察到息肉样病变完全闭塞，但血管网络仍保持通畅。在5年的随访期间，未观察到复发，视力提高到了1/10。
结论
根据我们的经验，光动力疗法取得了积极的效果，这表明它有可能成为处理这些病变并改善其预后的有用工具。
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