Princess Amalia Department of Paediatrics, Department of Neonatology, Isala, Zwolle, The Netherlands.
Radboud University Medical Center, Radboud Institute for Health Sciences, Amalia Children's Hospital, Department of Neonatology, Nijmegen, The Netherlands.
Acta Paediatr. 2018 Jun;107(6):981-989. doi: 10.1111/apa.14243. Epub 2018 Feb 21.
We compared three anthropometric charts to determine which provided the best predictions for adverse outcomes in very preterm small for gestational age (SGA) infants to address a lack of consensus on this subject.
This was a retrospective cohort study of infants born below 32 weeks, who were admitted to two-level three neonatal intensive care units in The Netherlands from 2008 to 2013. The birthweights of 1720 infants were classified as SGA using a conventional, gender-specific birthweight chart, based on births in The Netherlands between 2000 and 2007, a prescriptive, gender-specific birthweight chart, based on the same data but without risk factors for intrauterine growth restriction (IUGR), and a non-gender-specific foetal weight chart derived from American ultrasonographic measurements.
The conventional, prescriptive and foetal weight charts classified 126 (7.3%), 494 (28.7%) and 630 (36.6%) infants as SGA. The prescriptive chart, which excluded IUGR, identified 368 SGA infants with significantly increased risks of neonatal mortality and morbidity. The 136 SGA infants just classified by the American foetal weight chart were not at increased risk.
The prescriptive birthweight chart, which excluded infants with IUGR, was the most effective chart when it came to identifying clinically important risk increases in SGA infants.
我们比较了三种人体测量图表，以确定哪种图表能更好地预测极早产小于胎龄儿（SGA）的不良结局，因为目前在这个问题上缺乏共识。
这是一项回顾性队列研究，纳入了 2008 年至 2013 年在荷兰两家三级新生儿重症监护病房接受治疗的胎龄小于 32 周的婴儿。根据荷兰 2000 年至 2007 年的出生数据制定的传统性别特异性出生体重图表、不包含宫内生长受限（IUGR）风险因素的规定性别特异性出生体重图表和源自美国超声测量的非性别特异性胎儿体重图表，将 1720 名婴儿的出生体重分为 SGA。
传统、规定和胎儿体重图表分别将 126（7.3%）、494（28.7%）和 630（36.6%）名婴儿归类为 SGA。排除 IUGR 的规定图表确定了 368 名 SGA 婴儿，他们的新生儿死亡率和发病率风险显著增加。仅根据美国胎儿体重图表归类为 SGA 的 136 名婴儿风险并未增加。
排除 IUGR 婴儿的规定性出生体重图表在识别 SGA 婴儿的临床重要风险增加方面最有效。
