• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

锥形束计算机断层扫描作为根尖囊肿和肉芽肿鉴别诊断中一种无需活检的工具的可靠性：一项研究。

Reliability of cone beam computed tomography as a biopsy-independent tool in differential diagnosis of periapical cysts and granulomas: An Study.

作者信息

Chanani Ankit, Adhikari Haridas Das

机构信息

Department of Conservative Dentistry and Endodontics, Dr. R. Ahmed Dental College and Hospital, Kolkata, West Bengal, India.

出版信息

J Conserv Dent. 2017 Sep-Oct;20(5):326-331. doi: 10.4103/JCD.JCD_124_17.

DOI:10.4103/JCD.JCD_124_17
PMID:29386780
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5767827/
Abstract

BACKGROUND

Differential diagnosis of periapical cysts and granulomas is required as their treatment modalities are different.

AIM

The aim of this study was to evaluate the efficacy of cone beam computed tomography (CBCT) in the differential diagnosis of periapical cysts from granulomas.

SETTINGS AND DESIGN

A single-centered observational study was carried out in the Department of Conservative Dentistry and Endodontics, Dr. R. Ahmed Dental College and Hospital, using CBCT and dental operating microscope.

METHODS

Forty-five lesions were analyzed using CBCT scans. One evaluator analyzed each CBCT scan for the presence of the following six characteristic radiological features: cyst like-location, shape, periphery, internal structure, effect on the surrounding structures, and cortical plate perforation. Another independent evaluator analyzed the CBCT scans. This process was repeated after 6 months, and inter- and intrarater reliability of CBCT diagnoses was evaluated. Periapical surgeries were performed and tissue samples were obtained for histopathological analysis. To evaluate the efficacy, CBCT diagnoses were compared with histopathological diagnoses, and six receiver operating characteristic (ROC) curve analyses were conducted.

STATISTICAL ANALYSIS USED

ROC curve, Cronbach's alpha (α) test, and Cohen Kappa (κ) test were used for statistical analysis.

RESULTS

Both inter- and intrarater reliability were excellent (α = 0.94, κ = 0.75 and 0.77, respectively). ROC curve with regard to ≥4 positive findings revealed the highest area under curve (0.66).

CONCLUSION

CBCT is moderately accurate in the differential diagnosis of periapical cysts and granulomas.

摘要

背景

由于根尖囊肿和肉芽肿的治疗方式不同，因此需要对它们进行鉴别诊断。

目的

本研究的目的是评估锥形束计算机断层扫描（CBCT）在根尖囊肿与肉芽肿鉴别诊断中的效能。

设置与设计

在R. Ahmed博士牙科学院及医院的保守牙科与牙髓病科开展了一项单中心观察性研究，使用CBCT和牙科手术显微镜。

方法

使用CBCT扫描分析45个病变。一名评估者分析每个CBCT扫描，以确定是否存在以下六种特征性放射学表现：囊肿样位置、形状、边缘、内部结构、对周围结构的影响以及皮质板穿孔。另一名独立评估者分析CBCT扫描。6个月后重复此过程，并评估CBCT诊断的评估者间和评估者内可靠性。进行根尖手术并获取组织样本进行组织病理学分析。为评估效能，将CBCT诊断与组织病理学诊断进行比较，并进行六项受试者工作特征（ROC）曲线分析。

所用统计分析方法

使用ROC曲线、Cronbach's alpha（α）检验和Cohen Kappa（κ）检验进行统计分析。

结果

评估者间和评估者内可靠性均极佳（α分别为0.94，κ分别为0.75和0.77）。关于≥4项阳性发现的ROC曲线显示曲线下面积最高（0.66）。

结论

CBCT在根尖囊肿和肉芽肿的鉴别诊断中具有中等准确性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d429/5767827/f6ad34dcbdb9/JCD-20-326-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d429/5767827/74318e6147c6/JCD-20-326-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d429/5767827/ae4592e280f9/JCD-20-326-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d429/5767827/f6ad34dcbdb9/JCD-20-326-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d429/5767827/74318e6147c6/JCD-20-326-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d429/5767827/ae4592e280f9/JCD-20-326-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d429/5767827/f6ad34dcbdb9/JCD-20-326-g005.jpg

相似文献

1
Reliability of cone beam computed tomography as a biopsy-independent tool in differential diagnosis of periapical cysts and granulomas: An Study.锥形束计算机断层扫描作为根尖囊肿和肉芽肿鉴别诊断中一种无需活检的工具的可靠性：一项研究。
J Conserv Dent. 2017 Sep-Oct;20(5):326-331. doi: 10.4103/JCD.JCD_124_17.
2
Evaluation of the reliability and accuracy of using cone-beam computed tomography for diagnosing periapical cysts from granulomas.锥形束计算机断层扫描用于从肉芽肿中诊断根尖囊肿的可靠性和准确性评估。
J Endod. 2013 Dec;39(12):1485-90. doi: 10.1016/j.joen.2013.08.019. Epub 2013 Sep 27.
3
The detection of simulated periapical lesions in human dry mandibles with cone-beam computed tomography: a dose reduction study.应用锥形束 CT 检测人干燥下颌骨中的模拟根尖周病变：一项剂量减少研究。
Int Endod J. 2016 Nov;49(11):1095-1104. doi: 10.1111/iej.12565. Epub 2015 Nov 18.
4
Differentiation of periapical granuloma from radicular cyst using cone beam computed tomography images texture analysis.使用锥形束计算机断层扫描图像纹理分析鉴别根尖肉芽肿与根端囊肿
Heliyon. 2020 Oct 9;6(10):e05194. doi: 10.1016/j.heliyon.2020.e05194. eCollection 2020 Oct.
5
Reliability of Ultrasonography in differentially diagnosing periapical lesions of endodontic origin in comparison with Intra-oral periapical radiography and Cone-beam computed tomography: An study.与口腔根尖片和锥形束计算机断层扫描相比，超声在鉴别牙髓源性根尖周病变中的可靠性：一项研究。
J Conserv Dent. 2021 Sep-Oct;24(5):445-450. doi: 10.4103/jcd.jcd_254_21. Epub 2022 Mar 7.
6
Diagnostic accuracy of small volume cone beam computed tomography and intraoral periapical radiography for the detection of simulated external inflammatory root resorption.小视野锥形束 CT 与口腔根尖片诊断模拟外吸收性根面牙骨质吸收的准确性比较
Int Endod J. 2011 Feb;44(2):136-47. doi: 10.1111/j.1365-2591.2010.01819.x. Epub 2010 Nov 17.
7
Evaluation of pathologists (histopathology) and radiologists (cone beam computed tomography) differentiating radicular cysts from granulomas.评估病理学家（组织病理学）和放射科医生（锥形束 CT）在区分根尖囊肿和肉芽肿方面的表现。
J Endod. 2010 Mar;36(3):423-8. doi: 10.1016/j.joen.2009.11.005.
8
Noninvasive differential diagnosis of dental periapical lesions in cone-beam CT scans.锥形束CT扫描中牙体根尖周病变的无创鉴别诊断
Med Phys. 2015 Apr;42(4):1653-65. doi: 10.1118/1.4914418.
9
A comparison of cone beam computed tomography and periapical radiography for the detection of vertical root fractures in nonendodontically treated teeth.比较锥形束 CT 和根尖片在非根管治疗牙中检测垂直根折的效果。
Int Endod J. 2014 Aug;47(8):735-46. doi: 10.1111/iej.12209. Epub 2013 Dec 11.
10
Differential diagnosis of cemento-osseous dysplasia and periapical cyst using texture analysis of CBCT.应用 CBCT 纹理分析对骨-牙骨质瘤和根尖囊肿进行鉴别诊断。
BMC Oral Health. 2024 Apr 11;24(1):442. doi: 10.1186/s12903-024-04208-7.

引用本文的文献

1
Pseudo-color enhancement of CBCT images as a diagnostic tool for radicular cysts and periapical granulomas: A clinical feasibility study.CBCT图像的伪彩色增强作为诊断根端囊肿和根尖肉芽肿的工具：一项临床可行性研究。
Clin Oral Investig. 2025 Jul 3;29(7):371. doi: 10.1007/s00784-025-06425-y.
2
Accuracy of Ultrasound Imaging in the Differential Diagnosis of Inflammatory Radicular Cyst and Periapical Granuloma: A Systematic Review and Meta-Analysis of Operative Characteristics.超声成像在炎性根囊肿与根尖肉芽肿鉴别诊断中的准确性：手术特征的系统评价与Meta分析
Eur Endod J. 2025 Mar;10(2):104-115. doi: 10.14744/eej.2024.84755.
3

本文引用的文献

1
Ability of Cone-beam Computed Tomography to Detect Periapical Lesions That Were Not Detected by Periapical Radiography: A Retrospective Assessment According to Tooth Group.锥形束计算机断层扫描检测根尖片未发现的根尖周病变的能力：按牙组进行的回顾性评估
J Endod. 2016 Aug;42(8):1186-90. doi: 10.1016/j.joen.2016.04.026. Epub 2016 Jun 29.
2
Comparison between Radiographic (2-dimensional and 3-dimensional) and Histologic Findings of Periapical Lesions Treated with Apical Surgery.根尖手术治疗的根尖周病变的影像学（二维和三维）与组织学结果的比较
J Endod. 2015 Jun;41(6):804-11. doi: 10.1016/j.joen.2015.01.015. Epub 2015 Apr 8.
3
Uncertainty-based Active Learning by Bayesian U-Net for Multi-label Cone-beam CT Segmentation.
基于贝叶斯 U-Net 的不确定性主动学习在多标签锥形束 CT 分割中的应用。
J Endod. 2024 Feb;50(2):220-228. doi: 10.1016/j.joen.2023.11.002. Epub 2023 Nov 17.
4
The Paradigm of the Inflammatory Radicular Cyst: Biological Aspects to be Considered.炎性根侧囊肿的模式：需要考虑的生物学方面。
Eur Endod J. 2023 Jan;8(1):20-36. doi: 10.14744/eej.2022.26918.
5
The magnetic resonance imaging characteristics of radicular cysts and granulomas.神经根囊肿和肉芽肿的磁共振成像特征。
Dentomaxillofac Radiol. 2023 Feb;52(3):20220336. doi: 10.1259/dmfr.20220336. Epub 2023 Jan 23.
6
Reliability of Ultrasonography in differentially diagnosing periapical lesions of endodontic origin in comparison with Intra-oral periapical radiography and Cone-beam computed tomography: An study.与口腔根尖片和锥形束计算机断层扫描相比，超声在鉴别牙髓源性根尖周病变中的可靠性：一项研究。
J Conserv Dent. 2021 Sep-Oct;24(5):445-450. doi: 10.4103/jcd.jcd_254_21. Epub 2022 Mar 7.
7
Conservative Approach in the Management of Large Periapical Cyst-Like Lesions. A Report of Two Cases.保守治疗大型根尖周囊肿样病变。两例报告。
Medicina (Kaunas). 2021 May 14;57(5):497. doi: 10.3390/medicina57050497.
8
Endodontic Periapical Lesion: An Overview on the Etiology, Diagnosis and Current Treatment Modalities.牙髓根尖周病损：病因、诊断及当前治疗方法概述。
Eur Endod J. 2020 Jul 14;5(2):54-67. doi: 10.14744/eej.2020.42714. eCollection 2020.
9
Investigation of the effectiveness of CBCT and gray scale values in the differential diagnosis of apical cysts and granulomas.锥形束 CT 及灰度值在根尖囊肿和肉芽肿鉴别诊断中的效果研究。
Oral Radiol. 2021 Jan;37(1):109-117. doi: 10.1007/s11282-020-00459-6. Epub 2020 Jul 1.
10
Detection and measurements of apical lesions in the upper jaw by cone beam computed tomography and panoramic radiography as a function of cortical bone thickness.通过锥形束计算机断层扫描和全景放射摄影术检测和测量上颌骨的根尖病变，其与皮质骨厚度有关。
Clin Oral Investig. 2019 Nov;23(11):4067-4073. doi: 10.1007/s00784-019-02843-x. Epub 2019 Feb 22.
Relationship between Hounsfield Unit in CT Scan and Gray Scale in CBCT.
CT扫描中的亨氏单位与CBCT中的灰度之间的关系。
J Dent Res Dent Clin Dent Prospects. 2014 Spring;8(2):107-10. doi: 10.5681/joddd.2014.019. Epub 2014 Jun 11.
4
Evaluation of the reliability and accuracy of using cone-beam computed tomography for diagnosing periapical cysts from granulomas.锥形束计算机断层扫描用于从肉芽肿中诊断根尖囊肿的可靠性和准确性评估。
J Endod. 2013 Dec;39(12):1485-90. doi: 10.1016/j.joen.2013.08.019. Epub 2013 Sep 27.
5
Influence of cone beam CT scanning parameters on grey value measurements at an implant site.锥形束 CT 扫描参数对种植体部位灰度值测量的影响。
Dentomaxillofac Radiol. 2013;42(3):79884780. doi: 10.1259/dmfr/79884780. Epub 2012 Aug 29.
6
Accuracy of cone-beam computed tomography and periapical radiography in detecting small periapical lesions.锥形束 CT 与根尖片在检测微小根尖病变中的准确性。
J Endod. 2012 Jul;38(7):965-70. doi: 10.1016/j.joen.2012.03.001. Epub 2012 May 18.
7
Does a combination of two radiographs increase accuracy in detecting acid-induced periapical lesions and does it approach the accuracy of cone-beam computed tomography scanning?两张射线照片的组合是否能提高检测酸诱导根尖周病变的准确性，是否能接近锥形束计算机断层扫描的准确性？
J Endod. 2012 Feb;38(2):131-6. doi: 10.1016/j.joen.2011.10.013. Epub 2011 Dec 6.
8
Comparison of periapical radiography and limited cone-beam computed tomography in mandibular molars for analysis of anatomical landmarks before apical surgery.比较根尖片和锥形束 CT 在分析下颌磨牙根尖手术前解剖标志中的应用。
J Endod. 2011 Feb;37(2):151-7. doi: 10.1016/j.joen.2010.11.014.
9
Evaluation of pathologists (histopathology) and radiologists (cone beam computed tomography) differentiating radicular cysts from granulomas.评估病理学家（组织病理学）和放射科医生（锥形束 CT）在区分根尖囊肿和肉芽肿方面的表现。
J Endod. 2010 Mar;36(3):423-8. doi: 10.1016/j.joen.2009.11.005.
10
Nonsurgical root canal therapy of large cyst-like inflammatory periapical lesions and inflammatory apical cysts.大型囊肿样炎性根尖周病变和炎性根尖囊肿的非手术根管治疗
J Endod. 2009 May;35(5):607-15. doi: 10.1016/j.joen.2009.02.012.