Department of Lung Cancer Surgery, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China.
Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China.
Thorac Cancer. 2018 Feb;9(2):316-323. doi: 10.1111/1759-7714.12565. Epub 2017 Nov 28.
Primary pulmonary mucoepidermoid carcinoma (PMEC) is extremely rare. Herein, we report a case of a 71-year-old male patient with high-grade PMEC involving the right upper lobe that was successfully resected via lobectomy. As a result of invasion into the pleural and paratracheal lymph nodes, four cycles of adjuvant chemotherapy with paclitaxel and carboplatin were administered. There were no signs of relapse during 10 months of follow-up. Furthermore, we reviewed the literature and summarized the surgical approaches, prognostic factors, and underlying genetic mechanisms of PMEC, which will benefit clinical treatment.
原发性肺黏液表皮样癌（PMEC）极为罕见。本文报告了 1 例 71 岁男性患者，其右肺上叶发生高级别 PMEC，成功接受了肺叶切除术。由于侵犯了胸膜和气管旁淋巴结，患者接受了 4 个周期的紫杉醇和卡铂辅助化疗。在 10 个月的随访期间，没有复发的迹象。此外，我们还回顾了文献，总结了 PMEC 的手术方法、预后因素和潜在的遗传机制，这将有助于临床治疗。
