* Department of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, 1180 Nakasone-cho, Kita-ku, Sakai City, Osaka, 591-8555 Japan.
Jpn J Clin Oncol. 2014 May;44(5):493-6. doi: 10.1093/jjco/hyu016. Epub 2014 Mar 11.
A 59-year-old man was admitted to our hospital with dyspnea and cough. A large polypoid tumor was observed in the lower trachea and bronchoscopic polypectomy was performed using a snare to relieve symptoms. The tumor was diagnosed as a high grade mucoepidermoid carcinoma mainly by the histology of piecemeal specimens obtained by bronchoscopic resection. The primary lesion involved the trachea and the main bronchus, and there were multiple metastases in the lung. The patient was treated with the combination of carboplatin and paclitaxel. After four cycles of chemotherapy, the tumors were significantly reduced. He remains well without evidence of tumor progression for 25 months. This case suggests that the combination chemotherapy of carboplatin and paclitaxel can be an option for treatment of pulmonary mucoepidermoid carcinoma.
一位 59 岁男性因呼吸困难和咳嗽而入院。在较低的气管中观察到一个大的息肉样肿瘤，并使用圈套器进行支气管息肉切除术以缓解症状。肿瘤的组织学主要通过支气管切除获得的分片标本诊断为高级黏液表皮样癌。原发性病变累及气管和主支气管，肺部有多处转移。患者接受了卡铂和紫杉醇联合治疗。化疗四个周期后，肿瘤明显缩小。25 个月来，他情况良好，无肿瘤进展证据。该病例提示卡铂和紫杉醇联合化疗可能是治疗肺黏液表皮样癌的一种选择。
