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小儿神经囊尾蚴病:当前挑战与未来前景

Pediatric neurocysticercosis: current challenges and future prospects.

作者信息

Singhi Pratibha, Saini Arushi Gahlot

机构信息

Department of Pediatrics, Pediatric Neurology and Neurodevelopment Unit, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Pediatric Health Med Ther. 2016 Mar 8;7:5-16. doi: 10.2147/PHMT.S79058. eCollection 2016.

Abstract

Neurocysticercosis (NCC) is an acquired infection of the nervous system caused by encysted larvae of . It is a major cause of epilepsy in the tropics and the commonest cause of focal seizures in North Indian children. teniasis-cysticercosis is considered a parasitic "Neglected Tropical Diseases" endemic throughout Southeast Asia. NCC in children has pleomorphic manifestations depending on the location, number and viability of the cysts, and host response. Even with advancing knowledge of the disease manifestations, many aspects related to diagnosis and treatment, particularly in children, still remain controversial and pose challenges to clinical practice. There is no gold standard test to diagnose NCC and the management recommendations are still emerging. This review provides an overview of diagnosis of NCC in children and its management with special focus on current challenges and future prospects.

摘要

神经囊尾蚴病(NCC)是由猪带绦虫的囊尾蚴引起的一种后天性神经系统感染。它是热带地区癫痫的主要病因,也是印度北部儿童局灶性癫痫最常见的病因。猪带绦虫-囊尾蚴病被认为是一种遍布东南亚的寄生虫“被忽视的热带病”。儿童NCC的表现因囊肿的位置、数量和活力以及宿主反应而异。即使对疾病表现的认识不断提高,许多与诊断和治疗相关的方面,尤其是在儿童中,仍然存在争议,并给临床实践带来挑战。目前尚无诊断NCC的金标准检测方法,管理建议也仍在不断涌现。本综述概述了儿童NCC的诊断及其管理,特别关注当前的挑战和未来的前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfa3/5683283/5106f40bd13b/phmt-7-005Fig1.jpg

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