Pauwels R, Detiège J J
J Int Med Res. 1986;14(2):110-4. doi: 10.1177/030006058601400211.
Nine hundred and eleven patients were admitted to a multicentre trial with bacampicillin (Penglobe) in respiratory tract infections. Of these it was possible to evaluate 830 with respect to efficacy and side-effects. In most cases a dosage of 400 mg X 2 was used but in severe cases 800 mg X 2 was used. The clinical outcome was assessed as good for 79% of the patients, while 17% showed an improvement and 3% a failure. The tolerance was good with an over-all incidence of 8% side-effects, of which dyspepsia was the most common.
911名患者被纳入一项关于巴卡西林(朋格洛)治疗呼吸道感染的多中心试验。其中830名患者的疗效和副作用得以评估。多数情况下使用400毫克×2的剂量,但严重病例使用800毫克×2的剂量。79%的患者临床结果评估为良好,17%有改善,3%治疗失败。耐受性良好,副作用总发生率为8%,其中消化不良最为常见。