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生物信息学核心能力的发展与应用,以提高生物信息学培训和教育。

The development and application of bioinformatics core competencies to improve bioinformatics training and education.

机构信息

Computational Biology Division, Department of Integrative Biomedical Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

Department of Biological Sciences and Computational Biology Department, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America.

出版信息

PLoS Comput Biol. 2018 Feb 1;14(2):e1005772. doi: 10.1371/journal.pcbi.1005772. eCollection 2018 Feb.

Abstract

Bioinformatics is recognized as part of the essential knowledge base of numerous career paths in biomedical research and healthcare. However, there is little agreement in the field over what that knowledge entails or how best to provide it. These disagreements are compounded by the wide range of populations in need of bioinformatics training, with divergent prior backgrounds and intended application areas. The Curriculum Task Force of the International Society of Computational Biology (ISCB) Education Committee has sought to provide a framework for training needs and curricula in terms of a set of bioinformatics core competencies that cut across many user personas and training programs. The initial competencies developed based on surveys of employers and training programs have since been refined through a multiyear process of community engagement. This report describes the current status of the competencies and presents a series of use cases illustrating how they are being applied in diverse training contexts. These use cases are intended to demonstrate how others can make use of the competencies and engage in the process of their continuing refinement and application. The report concludes with a consideration of remaining challenges and future plans.

摘要

生物信息学被认为是众多生物医学研究和医疗保健职业道路的重要基础知识的一部分。然而,在该领域对于这些知识具体包括哪些内容以及如何最好地提供这些知识,尚未达成共识。这些分歧因需要生物信息学培训的人群范围广泛而变得更加复杂,这些人群具有不同的先前背景和预期的应用领域。国际计算生物学学会 (ISCB) 教育委员会课程工作组一直试图提供一个框架,根据一套跨越许多用户角色和培训计划的生物信息学核心能力来满足培训需求和课程设置。最初根据雇主和培训计划的调查制定的能力标准,通过多年的社区参与过程得到了完善。本报告介绍了这些能力标准的现状,并展示了一系列用例,说明它们如何在不同的培训环境中得到应用。这些用例旨在展示其他人如何利用这些能力标准,并参与到其持续改进和应用的过程中。报告最后考虑了剩余的挑战和未来计划。

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