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前哨淋巴结活检在头颈癌中的作用及其应用领域

The Role of Sentinel Lymph Node Biopsy in Head and Neck Cancers and Its Application Areas.

作者信息

Demir Deniz

机构信息

Department of Otorhinolaryngology, Sakarya University School of Medicine, Sakarya, Turkey.

出版信息

Turk Arch Otorhinolaryngol. 2016 Mar;54(1):35-38. doi: 10.5152/tao.2016.1129. Epub 2016 Apr 26.

DOI:10.5152/tao.2016.1129
PMID:29392013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5782973/
Abstract

The management of the clinically N0 neck in patients with head and neck cancers still remains controversial. Elective neck dissection is traditionally recommended when the subside of the head and neck, such as the oral cavity and supraglottic area, confers at least a 15-20% risk of lymphatic spread. However, elective neck dissection may cause an increase in patient morbidity and mortality rates. The emergence of sentinel lymph biopsy provides the possibility of accurate pathological staging of the cervical node with a less invasive procedure. The present review will summarize the role of sentinel lymph node biopsy and its application areas when evaluating occult metastases in patients with head and neck cancers.

摘要

头颈部癌症患者临床N0颈部的处理仍存在争议。传统上,当头颈部区域(如口腔和声门上区)存在至少15%-20%的淋巴转移风险时,建议进行选择性颈部清扫术。然而,选择性颈部清扫术可能会导致患者发病率和死亡率增加。前哨淋巴结活检的出现为通过侵入性较小的手术对颈部淋巴结进行准确病理分期提供了可能。本综述将总结前哨淋巴结活检在评估头颈部癌症患者隐匿性转移时的作用及其应用领域。

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本文引用的文献

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The Value of Sentinel Lymph Node Biopsy in Oral Cavity Cancers.前哨淋巴结活检在口腔癌中的价值
Turk Arch Otorhinolaryngol. 2015 Jun;53(2):62-66. doi: 10.5152/tao.2015.1178. Epub 2015 Jun 1.
2
Lateral neck sentinel lymph node biopsy in papillary thyroid carcinoma, is it really necessary? A randomized, controlled study.甲状腺乳头状癌侧颈前哨淋巴结活检真的有必要吗?一项随机对照研究。
Surgery. 2015 Mar;157(3):518-25. doi: 10.1016/j.surg.2014.10.013. Epub 2014 Nov 6.
3
Sentinel lymph node biopsy and risk factors for predicting metastasis in cutaneous squamous cell carcinoma.前哨淋巴结活检和预测皮肤鳞状细胞癌转移的危险因素。
Br J Dermatol. 2015 Apr;172(4):1029-36. doi: 10.1111/bjd.13508. Epub 2015 Mar 4.
4
Value of sentinel lymph node biopsy in papillary thyroid cancer: initial results of a prospective trial.前哨淋巴结活检在甲状腺乳头状癌中的价值:一项前瞻性试验的初步结果
Eur Arch Otorhinolaryngol. 2015 Apr;272(4):971-979. doi: 10.1007/s00405-014-3018-2. Epub 2014 Apr 3.
5
Diagnostic evaluation of sentinel lymph node biopsy in early head and neck squamous cell carcinoma: a meta-analysis.早期头颈部鳞状细胞癌前哨淋巴结活检的诊断评估:一项荟萃分析。
Head Neck. 2015 Jan;37(1):127-33. doi: 10.1002/hed.23526. Epub 2014 Jan 29.
6
Freehand SPECT-guided sentinel lymph node biopsy in early oral squamous cell carcinoma.徒手单光子发射计算机断层扫描引导下早期口腔鳞状细胞癌前哨淋巴结活检
Head Neck. 2014 Nov;36(11):E112-6. doi: 10.1002/hed.23596. Epub 2014 Jan 17.
7
Three-dimensional imaging and navigated sentinel node biopsy for primary parotid malignancy: new application in parotid cancer management.原发性腮腺恶性肿瘤的三维成像与导航前哨淋巴结活检:在腮腺癌管理中的新应用
Head Neck. 2014 Sep;36(9):E91-3. doi: 10.1002/hed.23560. Epub 2014 Jan 28.
8
Sentinel node identification in laryngeal cancer: Feasible in primary cancer with previously untreated neck.喉癌前哨淋巴结的识别:对于未经治疗的原发颈部肿瘤是可行的。
Oral Oncol. 2013 Feb;49(2):165-8. doi: 10.1016/j.oraloncology.2012.09.002. Epub 2012 Oct 1.
9
Sentinel node biopsy in early oral squamous cell carcinomas: a 10-year experience.早期口腔鳞状细胞癌前哨淋巴结活检:10 年经验。
Laryngoscope. 2012 Aug;122(8):1782-8. doi: 10.1002/lary.23383. Epub 2012 Jul 2.
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Sentinel lymph node biopsy versus selective neck dissection for detection of metastatic oral squamous cell carcinoma.前哨淋巴结活检与选择性颈部解剖术在检测口腔鳞状细胞癌转移中的比较。
Clin Exp Metastasis. 2012 Oct;29(7):693-8. doi: 10.1007/s10585-012-9492-2. Epub 2012 Jun 19.