选择性免疫球蛋白A缺乏症中的感音神经性听力损失
Sensorineural Hearing Loss in Selective Immunglobulin A Deficiency.
作者信息
Eşki Erkan, Usta Belgin Emine, Asilsoy Suna, Yılmaz İsmail
机构信息
Department of Otorhinolaryngology, Başkent University İzmir Hospital, İzmir, Turkey.
Department of Pediatrics, Başkent University Adana Hospital, Adana, Turkey.
出版信息
Turk Arch Otorhinolaryngol. 2017 Mar;55(1):31-33. doi: 10.5152/tao.2017.1923. Epub 2017 Mar 1.
OBJECTIVE
To assess hearing functions in pediatric patients with selective immunoglobulin A (IgA) deficiency (SIGAD).
METHODS
Pure-tone audiometry, acoustic impedance, otoacoustic emission, and brainstem audiometric measurements were taken during a non-infectious period in 28 patients with SIGAD and 28 healthy children with normal otoscopic examination. The results of the hearing tests were compared between the two groups.
RESULTS
Two male patients and one female patient in the SIGAD group were found to have sensorineural hearing loss (SNHL). However, a comparison of the average pure tone cut-off values at 0.5, 1, 2, and 4 kHz did not reveal any statistically significant difference between the groups (p>0.05).
CONCLUSION
Pediatric patients with SIGAD may exhibit SNHL at certain frequencies and require follow-up for the potential development of hearing loss.
目的
评估选择性免疫球蛋白A（IgA）缺乏症（SIGAD）患儿的听力功能。
方法
对28例SIGAD患儿和28例耳镜检查正常的健康儿童在非感染期进行纯音听力测定、声阻抗、耳声发射和脑干听力测量。比较两组听力测试结果。
结果
SIGAD组中发现2例男性患者和1例女性患者有感音神经性听力损失（SNHL）。然而，两组在0.5、1、2和4 kHz处的平均纯音截止值比较未发现有统计学意义的差异（p>0.05）。
结论
SIGAD患儿在某些频率可能表现出SNHL，需要对听力损失的潜在发展进行随访。
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