Huang Qiushi, Mao Sifeng, Khan Mashooq, Zhou Lin, Lin Jin-Ming
Department of Chemistry, Beijing Key Laboratory of Micronalytical Methods and Instrumentation, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing 100084, China.
Chem Commun (Camb). 2018 Mar 8;54(21):2595-2598. doi: 10.1039/c7cc09608a.
This study describes a novel Dean flow assisted cell ordering system which is connected to an electrospray ionization-mass spectrometer for the detection of lipids in a single-cell. This platform provides a facile method for direct analysis of label-free lipids in single-cells and significantly improves the efficiency of single-cell mass spectrometry.
本研究描述了一种新型的Dean流辅助细胞排序系统，该系统与电喷雾电离质谱仪相连，用于检测单细胞中的脂质。该平台为直接分析单细胞中无标记脂质提供了一种简便方法，并显著提高了单细胞质谱分析的效率。
