Morita Junya, Aoyama Toru, Amano Shinya, Maezawa Yukio, Sawazaki Sho, Numata Masakatsu, Sato Tsutomu, Oshima Takashi, Yamada Takanobu, Hayashi Tsutomu, Yamanaka Shouji, Yukawa Norio, Rino Yasushi, Masuda Munetaka
Dept. of Surgery, Yokohama City University Hospital.
Gan To Kagaku Ryoho. 2017 Nov;44(12):1393-1395.
A 65-year-old female received distal gastrectomy for gastric cancer.The pathological diagnosis was well differentiated adenocarcinoma(tub1), type 2, pT3, ly: 1, v: 1, N0, H0, P0, M0, CY0, pStage II A.She had been observed without adjuvant chemotherapy.Five years after the resection, umbilical tumor and intraperitoneal nodules were detected by computed tomography. Needle biopsy cytology of umbilical tumor revealed metastasis from gastric cancer.Based on the diagnosis of umbilical metastasis and peritoneal dissemination, S-1(80mg/m / 2, day 1-21)and CDDP(60mg/m2, day 8)were administered for 7 courses.Because of diarrhea(Grade 3), chemotherapy was changed to paclitaxel(80mg/m2, day 1, 8, 15).To date, the patient has undergone 33 courses of paclitaxel.The response evaluation is complete response and no other metastases are detected.She has survived more than 3 years from recurrence of gastric cancer.We report a long-surviving case of umbilical metastasis from post operative gastric cancer with chemotherapy.
一名65岁女性因胃癌接受了远端胃切除术。病理诊断为高分化腺癌（tub1），2型，pT3，ly: 1，v: 1，N0，H0，P0，M0，CY0，pII A期。她未接受辅助化疗，一直在观察。切除术后五年，通过计算机断层扫描检测到脐部肿瘤和腹腔内结节。脐部肿瘤的针吸活检细胞学检查显示为胃癌转移。基于脐部转移和腹膜播散的诊断，给予S-1（80mg/m²，第1 - 21天）和顺铂（60mg/m²，第8天），共进行7个疗程。由于腹泻（3级），化疗改为紫杉醇（80mg/m²，第1、8、15天）。迄今为止，该患者已接受33个疗程的紫杉醇治疗。疗效评估为完全缓解，未检测到其他转移灶。自胃癌复发以来，她已存活超过3年。我们报告了一例术后胃癌脐部转移经化疗后长期存活的病例。
