《秀丽隐杆线虫中工程重组平衡器工具包》。
A Toolkit of Engineered Recombinational Balancers in C. elegans.
机构信息
Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
出版信息
Trends Genet. 2018 Apr;34(4):253-255. doi: 10.1016/j.tig.2018.01.009. Epub 2018 Jan 31.
Abstract
Dejima and colleagues report using CRISPR/Cas9 to generate a new collection of greatly improved balancer chromosomes in the standard laboratory nematode Caenorhabditis elegans, using methods previously reported by the same laboratory, expanding the set of C. elegans balancers to cover nearly 90% of coding genes.
摘要
德岛和同事们报告称，他们使用 CRISPR/Cas9 在标准实验室线虫秀丽隐杆线虫中生成了一组经过极大改良的新平衡染色体，使用的方法是同一实验室之前报告的方法，从而将秀丽隐杆线虫的平衡染色体集扩展到几乎涵盖 90%的编码基因。
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