García-Hermoso Antonio, Martínez-Vizcaíno Vicente, Gomez-Marcos Manuel Ángel, Cavero-Redondo Iván, Recio-Rodriguez José Ignacio, García-Ortiz Luis
Laboratorio de Ciencias de la Actividad Física, el Deporte y la Salud, Facultad de Ciencias Médicas, Universidad de Santiago de Chile, USACH, Chile.
Social and Health Care Research Center, University of Castilla-La Mancha, Cuenca, Spain; Universidad Autónoma de Chile, Talca, Chile.
J Stroke Cerebrovasc Dis. 2018 May;27(5):1386-1394. doi: 10.1016/j.jstrokecerebrovasdis.2017.12.031. Epub 2018 Feb 1.
Studies concerning ideal cardiovascular (CV) health and its relationship with arterial stiffness are lacking. This study examined the association between arterial stiffness with ideal CV health as defined by the American Heart Association, across age groups and gender.
The cross-sectional study included 1365 adults. Ideal CV health was defined as meeting ideal levels of the following components: 4 behaviors (smoking, body mass index, physical activity, and Mediterranean diet adherence) and 3 factors (total cholesterol, blood pressure, and glycated hemoglobin). Patients were grouped into 3 categories according to their number of ideal CV health metrics: ideal (5-7 metrics), intermediate (3-4 metrics), and poor (0-2 metrics). We analyzed the pulse wave velocity (PWV), the central and radial augmentation indexes, and the ambulatory arterial stiffness index (AASI).
The ideal CV health profile was inversely associated with lower arterial radial augmentation index and AASI in both genders, particularly in middle-aged (45-65 years) and in elderly subjects (>65 years). Also in elderly subjects, adjusted models showed that adults with at least 3 health metrics at ideal levels had significantly lower PWV than those with 2 or fewer ideal health metrics.
An association was found between a favorable level of ideal CV health metrics and lower arterial stiffness across age groups.
关于理想心血管（CV）健康及其与动脉僵硬度关系的研究尚缺。本研究探讨了美国心脏协会定义的理想CV健康与动脉僵硬度之间在不同年龄组和性别中的关联。
这项横断面研究纳入了1365名成年人。理想CV健康定义为达到以下各组成部分的理想水平：4种行为（吸烟、体重指数、身体活动和遵循地中海饮食）和3种因素（总胆固醇、血压和糖化血红蛋白）。患者根据其理想CV健康指标的数量分为3类：理想（5 - 7项指标）、中等（3 - 4项指标）和较差（0 - 2项指标）。我们分析了脉搏波速度（PWV）、中心和桡动脉增强指数以及动态动脉僵硬度指数（AASI）。
理想CV健康状况与较低的桡动脉增强指数和AASI呈负相关，在男女两性中均如此，尤其是在中年（45 - 65岁）和老年受试者（>65岁）中。同样在老年受试者中，校正模型显示理想水平至少有3项健康指标的成年人的PWV显著低于理想健康指标为2项或更少的成年人。
在不同年龄组中，发现理想CV健康指标的良好水平与较低的动脉僵硬度之间存在关联。
