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更高的总体力活动与瑞典年轻成年人的动脉僵硬度降低有关:横断面生活方式、生物标志物和动脉粥样硬化研究。

Higher Total Physical Activity is Associated with Lower Arterial Stiffness in Swedish, Young Adults: The Cross-Sectional Lifestyle, Biomarkers, and Atherosclerosis Study.

机构信息

Cardiovascular Research Center, Faculty of Medicine and Health, Örebro University, Örebro, 70182, Sweden.

Department of Physical Activity and Health, The Swedish School of Sport and Health Sciences, GIH, Stockholm, 11433, Sweden.

出版信息

Vasc Health Risk Manag. 2021 Apr 29;17:175-185. doi: 10.2147/VHRM.S283211. eCollection 2021.

DOI:10.2147/VHRM.S283211
PMID:33953561
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8092620/
Abstract

PURPOSE

Arterial stiffness describes the rigidity of the arterial walls and is associated with risk factors for cardiovascular disease (CVD). Arterial stiffness predicts future events and mortality, and the predictive value is stronger in younger versus older subjects. The aims of the present study were, firstly, to present data on physical activity (PA) and time spent sedentary, in the population of Swedish, young adults. Secondly, to explore the association between PA and arterial stiffness.

MATERIAL AND METHODS

Self-reported healthy, non-smoking, Swedish, young adults, 18-25 years old, participated in the cross-sectional Lifestyle, Biomarkers and Atherosclerosis (LBA) study. The daily PA was objectively measured with an accelerometer for 1 week. Of the 834 participants, 658 individuals had valid registrations. The arterial stiffness measures, pulse wave velocity (PWV) and augmentation index (AIx) were measured with applanation tonometry.

RESULTS

Women were on overall more physically active than men, they spent 214 min/day in light PA (LPA) compared to men who spent 202 min/day. Women took significantly more steps per day than men, 7796 vs 7336 steps/day, and spent less time sedentary, 523 min/day, compared to men who spent 547 min/day sedentary. In total, 76% of the individuals spent on average at least 30 minutes per day in the recommended moderate and vigorous PA (MVPA). Lower arterial stiffness was associated with more MVPA and total PA in the total population.

CONCLUSION

We conclude that in this age group of young, self-reported healthy adults 18-25 years, it is important to highlight the health-enhancing possibilities of time spent in physical activity on the vascular function, measured as PWV and AIx. It is of high relevance in a public health perspective to expand preventive efforts beyond the high-risk groups and encourage young adults to be physically active.

摘要

目的

动脉僵硬度描述了动脉壁的刚性,与心血管疾病(CVD)的危险因素有关。动脉僵硬度可预测未来的事件和死亡率,并且在年轻受试者中比在老年受试者中的预测价值更强。本研究的目的首先是介绍瑞典年轻成年人的体力活动(PA)和久坐时间的数据。其次,探讨 PA 与动脉僵硬度之间的关系。

材料和方法

自我报告健康、不吸烟的瑞典年轻成年人,18-25 岁,参加了横断面生活方式、生物标志物和动脉粥样硬化(LBA)研究。每周用加速度计对日常 PA 进行客观测量。在 834 名参与者中,有 658 名个体的记录有效。使用平板血压计测量动脉僵硬度指标脉搏波速度(PWV)和增强指数(AIx)。

结果

女性的总体体力活动水平高于男性,女性每天进行 214 分钟的低强度 PA(LPA),而男性每天进行 202 分钟。女性每天的步数明显多于男性,分别为 7796 步和 7336 步,每天的久坐时间也更少,为 523 分钟,而男性每天的久坐时间为 547 分钟。总的来说,76%的个体平均每天至少有 30 分钟进行推荐的中高强度体力活动(MVPA)。在总人群中,较低的动脉僵硬度与更多的 MVPA 和总 PA 相关。

结论

我们的结论是,在 18-25 岁的年轻、自我报告健康的成年人中,强调在血管功能方面,即通过 PWV 和 AIx 测量,体力活动所花费的时间对健康的有益作用非常重要。从公共卫生的角度来看,扩大预防工作范围,超越高危人群,并鼓励年轻人积极参与体力活动具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcbf/8092620/c9b114b14b31/VHRM-17-175-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcbf/8092620/8389ba5593f1/VHRM-17-175-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcbf/8092620/c9b114b14b31/VHRM-17-175-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcbf/8092620/8389ba5593f1/VHRM-17-175-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcbf/8092620/c9b114b14b31/VHRM-17-175-g0002.jpg

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