Heart Transplant Program, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, USA; Ted Rogers Centre of Excellence in Heart Function, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Ted Rogers Centre of Excellence in Heart Function, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
J Heart Lung Transplant. 2018 May;37(5):564-567. doi: 10.1016/j.healun.2017.12.014. Epub 2017 Dec 20.
The Public Health Service has defined 12 criteria of increased-risk (PHS-IR) for transmissible viral infections in potential organ donors where clinicians are required to document informed consent. Over the last decade, there has been a near tripling of PHS-IR donor organs in the United States. In light of the paucity in guidelines and consensus statements to guide clinicians on how to provide informed consent to potential recipients, using a typical case, we provide an overview including: how to effectively communicate infectious risk, whether clinicians should decline PHS-IR organs, the need to standardize disclosure practice across centers and finally how much information about the donor should be communicated to the transplant candidate. Many patients can be empowered by involving them in shared decision making to understand the minimal risk associated with the use of PHS-IR organs; an important step in improving donor utilization.
美国公共卫生署(Public Health Service)定义了 12 项潜在器官捐献者传染性病毒感染的高风险标准(PHS-IR),临床医生需要记录知情同意书。在过去十年中,美国 PHS-IR 供体器官的数量几乎增加了两倍。鉴于缺乏指导临床医生如何向潜在受者提供知情同意的指南和共识声明,我们使用一个典型案例提供了一个概述,包括:如何有效地沟通感染风险,临床医生是否应该拒绝 PHS-IR 器官,是否需要在各中心之间标准化披露实践,以及应该向移植候选人传达多少有关供体的信息。通过让他们参与共同决策,许多患者可以获得授权,以了解使用 PHS-IR 器官相关的最小风险;这是提高供体利用率的重要一步。