Singh Sheldon M, Webster Lauren, Qiu Feng, Austin Peter C, Ko Dennis T, Tu Jack V, Wijeysundera Harindra C
Schulich Heart Centre and The Department of Medicine, Sunnybrook Health Sciences Centre, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Institute for Clinical Evaluative Sciences (ICES), Toronto, Ontario, Canada.
Am J Cardiol. 2018 Apr 1;121(7):830-835. doi: 10.1016/j.amjcard.2017.12.031. Epub 2018 Jan 9.
Few patients with atrial fibrillation (AF) receive care by cardiac electrophysiologists. Although previous work has highlighted differential care for patients with AF treated by electrophysiologists, it is unclear whether this is associated with improved clinical outcomes. This retrospective population-level propensity score-matched cohort study included patients aged 20 to 80 years with new-onset AF presenting to an emergency department (ED) in Ontario, Canada, between 2010 and 2012. Patients were followed until March 31, 2015. Patients who saw an electrophysiologist within 1 year of the index ED visit were matched to patients who did not see an electrophysiologist. Linked administrative databases were used for cohort construction and allow 1-year follow-up to assess for the clinical end points of all-cause mortality and hospitalization for AF, heart failure, bleeding, and stroke. A total of 5,221 unique pairs of patients were matched. One hundred seventeen patients (2.2%) in the electrophysiologist cohort underwent an AF ablation procedure during the 1-year follow-up period. All-cause mortality (hazard ratio [HR] = 1.1, p = 0.17) and stroke (HR = 1.4, p = 0.09) were not significantly different between the 2 groups. Hospitalization for AF (HR = 1.4, p <0.001), bleeding (HR = 1.5, p = 0.0001), and congestive heart failure (HR = 1.5, p <0.0001) was increased in the group that saw an electrophysiologist. In conclusion, electrophysiologist care was not associated with improved clinical outcomes in patients with new-onset AF.
很少有房颤(AF)患者接受心脏电生理学家的治疗。尽管先前的研究强调了电生理学家对房颤患者的差异化治疗,但尚不清楚这是否与改善临床结局相关。这项回顾性人群水平倾向评分匹配队列研究纳入了2010年至2012年间在加拿大安大略省急诊科就诊的20至80岁新发房颤患者。对患者进行随访至2015年3月31日。将在首次急诊科就诊后1年内看过电生理学家的患者与未看过电生理学家的患者进行匹配。使用关联的行政数据库进行队列构建,并进行1年随访以评估全因死亡率以及房颤、心力衰竭、出血和中风住院等临床终点。总共匹配了5221对独特的患者。电生理学家队列中的117名患者(2.2%)在1年随访期内接受了房颤消融手术。两组之间的全因死亡率(风险比[HR]=1.1,p=0.17)和中风(HR=1.4,p=0.09)无显著差异。看过电生理学家的组中,房颤住院(HR=1.4,p<0.001)、出血(HR=1.5,p=0.0001)和充血性心力衰竭(HR=1.5,p<0.0001)有所增加。总之,电生理学家的治疗与新发房颤患者临床结局的改善无关。