Liu Z, Tseng C C, Zhao Z H, Li J, Wang B, Yu Y, Qian B P, Sun X, Qiu Y, Zhu Z Z
Department of Spine Surgery, Drum Tower Hospital, Medical School of Nanjing University, Nanjing 210008, China.
Zhonghua Wai Ke Za Zhi. 2018 Feb 1;56(2):139-146. doi: 10.3760/cma.j.issn.0529-5815.2018.02.012.
To compare the clinical outcome and health related quality of life(HRQoL)of patients with degenerative spinal deformity who underwent spino-pelvic fixation utilized second sacral alar-iliac(S(2)AI)with patient utilized traditional iliac screw(IS). Patients diagnosed as degenerative spinal deformity who underwent spino-pelvic fixation utilized either S(2)AI screw or Iliac screw at Department of Spine Surgery of Drum Tower hospital from January 2013 to January 2016 were retrospectively analyzed. Patients were divided into two groups according to the pelvic fixation technique. Cobb's angle, coronal balance distance(CBD), regional kyphosis(RK), sagittal vertical axis(SVA)were recorded at pre-operation, post-operation and last follow up. The MOS item short from the health survey(SF-36), visual analogue scale(VAS), Oswestry disability index(ODI) were also recorded at pre-operation and last follow up. Five physical examinations were administered to all patient at the last follow up to diagnose sacroiliac joint dysfunction, three tests resulting positive were regarded as dysfunction. Repeated measurement analysis of variance, -test or non-parametric test was used to analyzed the data, respectively. A total of 22 patients who met the inclusion were recruited in this study. Fourteen patients were utilized S(2)AI screw and 8 patients were utilized iliac screw.There were no significant differences in age, gender, follow up time between two groups. Cobb's angle, CBD, RK, SVA at pre- and post-operation and last follow up showed no significant difference between two groups.SF-36, ODI, VAS at pre-operation and last follow up showed no significant difference between two groups. Compared with baseline, Cobb's angle(44.4°±14.0° . 20.2°±7.2° . 18.3°±7.1°), C(7)PL-CSVL((25.3±16.0)mm . (10.3±5.7)mm . (9.2±4.2)mm), RK(33.0°(-12.0°, 50.0°) . 20.0°(-33.0°, 8.5°) . -19.0°(-29.0°, 19.0°)), SVA((31.5±34.4)mm . (12.1±8.4)mm . (10.9±7.2)mm), SF36-physical function summary(PCS)(39.8±14.3 . 68.2±21.5), SF36-mental component summary(MCS)(44.9±14.8 . 73.9±19.9), ODI(37.7±16.9 . 19.8±15.8), VAS(4.8±2.1 . 1.8±0.9) were significantly improved postoperatively in S(2)AI group(<0.05). In the IS group, compared with baseline, Cobb's angle(54.3°±18.3° . 26.1°±13.2° . 25.6°±18.3°), C(7)PL-CSVL((31.0±16.0)mm . (13.9±7.0)mm . (12.4±6.6)mm), RK (47.0°(15.0°, 57.0°) . 4.0°(-10.0°, 16.0°) . 7.0°(-9.0°, 12.0°)), SVA((27.1±23.9)mm .(13.1±7.5)mm . (13.6±6.0)mm), SF36-PCS(29.7±7.1 . 61.1±11.2), SF36-MCS(35.9±7.1 . 64.0±11.1), ODI(48.6±13.4 . 19.0±10.7), VAS(4.9±1.8 . 2.6±1.3) were also significantly improved postoperatively(all <0.05). There were two patients need revision surgery in the IS group due to the instrumentation-related complication. None of the patients in the S(2)AI group needed revision surgery. There were no instances of sacroiliac joint dysfunction in both groups at last follow up. Spino-pelvic fixation utilizing S(2)AI screw could provide similar correction rate to iliac screw and the sacroiliac joint penetration due to S(2)AI won't affect the HRQoL in patient with degenerative deformity who utilized S(2)AI.
比较接受第二骶椎翼-髂骨(S(2)AI)椎骨盆固定术与接受传统髂骨螺钉(IS)固定术的退变性脊柱畸形患者的临床疗效及健康相关生活质量(HRQoL)。回顾性分析2013年1月至2016年1月在鼓楼医院脊柱外科接受椎骨盆固定术,采用S(2)AI螺钉或髂骨螺钉治疗的退变性脊柱畸形患者。根据骨盆固定技术将患者分为两组。记录术前、术后及末次随访时的Cobb角、冠状面平衡距离(CBD)、节段性后凸(RK)、矢状面垂直轴(SVA)。术前及末次随访时还记录健康调查简表(SF-36)、视觉模拟评分法(VAS)、Oswestry功能障碍指数(ODI)。在末次随访时对所有患者进行五项体格检查以诊断骶髂关节功能障碍,三项检查结果为阳性则视为功能障碍。分别采用重复测量方差分析、t检验或非参数检验分析数据。本研究共纳入22例符合纳入标准的患者。14例患者采用S(2)AI螺钉,8例患者采用髂骨螺钉。两组患者在年龄、性别、随访时间方面无显著差异。两组术前、术后及末次随访时的Cobb角、CBD、RK、SVA均无显著差异。两组术前及末次随访时的SF-36、ODI、VAS均无显著差异。与基线相比,S(2)AI组术后Cobb角(44.4°±14.0°、20.2°±7.2°、18.3°±7.1°)、C(7)PL-CSVL((25.3±16.0)mm、(10.3±5.7)mm、(9.2±4.2)mm)、RK(33.0°(-12.0°,50.0°)、20.0°(-33.0°,8.5°)、-19.0°(-29.0°,19.0°))、SVA((31.5±34.4)mm、(12.1±8.4)mm、(10.9±7.2)mm)、SF36-生理功能总结(PCS)(39.8±14.3、68.2±21.5)、SF36-心理成分总结(MCS)(44.9±14.8、73.9±19.9)、ODI(37.7±16.9、19.8±15.8)、VAS(4.8±2.1、1.8±0.9)均显著改善(P<0.05)。在IS组,与基线相比,Cobb角(54.3°±18.3°、26.1°±13.2°、25.6°±18.3°)、C(7)PL-CSVL((31.0±16.0)mm、(13.9±7.0)mm、(12.4±6.6)mm)、RK(47.0°(15.0°,57.0°)、4.0°(-10.0°,16.0°)、7.0°(-9.0°,12.0°))、SVA((27.1±23.9)mm、(13.1±7.5)mm、(13.6±6.0)mm)、SF36-PCS(29.7±7.1、61.1±11.2)、SF36-MCS(35.9±7.1、64.0±11.1)、ODI(48.6±13.4、19.0±10.7)、VAS(4.9±1.8、2.6±1.3)术后也均显著改善(均P<0.05)。IS组有2例患者因器械相关并发症需要翻修手术。S(2)AI组无患者需要翻修手术。末次随访时两组均无骶髂关节功能障碍病例。采用S(2)AI螺钉的椎骨盆固定术与髂骨螺钉固定术可提供相似的矫正率,且S(2)AI导致的骶髂关节穿透不影响采用S(2)AI治疗的退变性畸形患者的HRQoL。