环孢素的作用与毒性。
Action and toxicity of cyclosporine.
作者信息
Bennett W M, Norman D J
出版信息
Annu Rev Med. 1986;37:215-24. doi: 10.1146/annurev.me.37.020186.001243.
Abstract
Cyclosporine is a potent new immunosuppressive agent that has proven particularly useful in organ transplantation. The unique action of the drug on T-cell immunity without myelosuppression is summarized. Cyclosporine pharmacology and adverse reactions, particularly nephrotoxicity, are reviewed in this paper.
摘要
环孢素是一种强效的新型免疫抑制剂，已证明在器官移植中特别有用。总结了该药物对T细胞免疫的独特作用且无骨髓抑制作用。本文综述了环孢素的药理学及不良反应，尤其是肾毒性。
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