Department of Biological and Pharmaceutical Sciences, Institute of Technology Tralee, Tralee, Co. Kerry, Ireland, V92 CX88.
Animal & Grassland Research and Innovation Centre, Teagasc, Moorepark, Fermoy, Co. Cork, Ireland, P61 C996.
J Dairy Sci. 2018 Apr;101(4):3205-3212. doi: 10.3168/jds.2017-13445. Epub 2018 Feb 2.
Calf mortality and morbidity commonly occurs within the first month of life postpartum. Standard health ranges are invaluable aids in diagnostic veterinary medicine to confirm normal or the degree and nature of abnormal parameters in (sub)clinically ill animals. Extensive research has indicated significant differences between the physiologies of neonate and adult cattle, particularly for blood parameters such as pH, base excess, anion gap, and bicarbonate (HCO). The objective of this research was to determine the influence of age, sex, and breed type, in addition to environmental factors, on the normal blood gas profiles of neonatal calves, and thus develop a scientifically validated reference range accounting for any significant factors. The study was conducted on healthy neonatal calves (n = 288), and completed over a 2-yr period. Individual calf blood gas analysis was conducted for parameters of pH, base excess, Na, K, Ca, Cl, glucose, total hemoglobin, HCO, pCO, anion gap, strong ion difference, and hematocrit levels. Regression procedures examined the combined effect of year, farm, age, breed type, sex, and hours postfeeding on each variable. Significant effects were observed for age, sex, and breed type on several of the blood gas variables. Furthermore, year, farm, and hours postfeeding appeared to have less of an influence on neonatal bovine blood gas profiles. Consequently, specific ranges based on the neonate's age, sex, and breed type will allow for more detailed and accurate diagnosis of health and ill health in neonatal calves.
犊牛的病死率和发病率通常发生在产后第一个月内。标准健康范围是兽医诊断学中非常有价值的辅助手段，可以确认（亚）临床患病动物的正常或异常参数的程度和性质。大量研究表明，新生牛和成年牛的生理学有很大差异，特别是对于血液参数，如 pH 值、碱剩余、阴离子间隙和碳酸氢盐（HCO）。本研究旨在确定年龄、性别和品种类型以及环境因素对新生犊牛正常血气谱的影响，从而制定出科学验证的参考范围，以考虑任何重要因素。该研究在 2 年内对 288 头健康的新生犊牛进行了研究。对每头犊牛的血液气体参数（pH 值、碱剩余、Na、K、Ca、Cl、葡萄糖、总血红蛋白、HCO、pCO、阴离子间隙、强离子差和红细胞压积水平）进行了个体分析。回归程序检查了年、农场、年龄、品种类型、性别和进食后时间对每个变量的综合影响。年龄、性别和品种类型对几个血气变量有显著影响。此外，年、农场和进食后时间对新生牛血气谱的影响似乎较小。因此，基于新生犊牛的年龄、性别和品种类型的特定范围将允许对新生犊牛的健康和患病情况进行更详细和准确的诊断。
