Mohammadi Fatemeh, Amirzadeh Iranagh Jamileh, Motalebi Seyedeh Ameneh, Hamid Tengku Aizan
Social Determinants of Health Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Department of Public Health, Urmia University of Medical Sciences, Urmia, Iran.
Women Health. 2019 Feb;59(2):145-154. doi: 10.1080/03630242.2018.1434592. Epub 2018 Jul 24.
This study examined the relationship between reproductive characteristics and bone mineral density (BMD) in postmenopausal women who had been referred to the menopause clinics of the National Population and Family Development Board and of the Hospital Kuala Lumpur from July 2011 to January 2012. The participants of this study were 201 postmenopausal Malaysian women aged 45-71 years. Some socio-demographic, lifestyle, and reproductive factors were recorded. Calcaneal BMD was measured by quantitative ultra-sonography. Correlations of reproductive factors with BMD were assessed by Pearson's correlation test and multiple regression analysis. Age at menopause was not significantly correlated with BMD, while the years after menopause, age at the first menstrual period, number of pregnancies, and total lactation periods were inversely correlated with it. Among reproductive factors, only the association between lactation duration and BMD remained significant after adjusting for age, body mass index, activity, and calcium intake. The results indicated that except for prolonged total time of lactation, other reproductive factors were not significantly associated with BMD in postmenopausal women.
本研究调查了2011年7月至2012年1月期间转诊至国家人口与家庭发展委员会及吉隆坡医院更年期诊所的绝经后女性的生殖特征与骨密度（BMD）之间的关系。本研究的参与者为201名年龄在45 - 71岁之间的马来西亚绝经后女性。记录了一些社会人口统计学、生活方式和生殖因素。通过定量超声测量跟骨骨密度。通过Pearson相关检验和多元回归分析评估生殖因素与骨密度的相关性。绝经年龄与骨密度无显著相关性，而绝经年限、初潮年龄、怀孕次数和总哺乳期与之呈负相关。在生殖因素中，调整年龄、体重指数、活动量和钙摄入量后，仅哺乳期与骨密度之间的关联仍然显著。结果表明，除总哺乳期延长外，其他生殖因素与绝经后女性的骨密度无显著关联。
