标准化回肠可消化缬氨酸：赖氨酸剂量反应在商业条件下 25-45 公斤猪中的影响。

Standardized ileal digestible valine:lysine dose response effects in 25- to 45-kg pigs under commercial conditions.

机构信息

Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Manhattan, KS.

Department of Animal Sciences and Industry, College of Agriculture, Manhattan, KS.

出版信息

J Anim Sci. 2018 Mar 6;96(2):591-599. doi: 10.1093/jas/skx059.

DOI:10.1093/jas/skx059

PMID:29401290

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6140919/

Abstract

Two experiments were conducted to estimate the standardized ileal digestible valine:lysine (SID Val:Lys) dose response effects in 25- to 45-kg pigs under commercial conditions. In experiment 1, a total of 1,134 gilts (PIC 337 × 1050), initially 31.2 kg ± 2.0 kg body weight (BW; mean ± SD) were used in a 19-d growth trial with 27 pigs per pen and seven pens per treatment. In experiment 2, a total of 2,100 gilts (PIC 327 × 1050), initially 25.4 ± 1.9 kg BW were used in a 22-d growth trial with 25 pigs per pen and 12 pens per treatment. Treatments were blocked by initial BW in a randomized complete block design. In experiment 1, there were a total of six dietary treatments with SID Val at 59.0, 62.5, 65.9, 69.6, 73.0, and 75.5% of Lys and for experiment 2 there were a total of seven dietary treatments with SID Val at 57.0, 60.6, 63.9, 67.5, 71.1, 74.4, and 78.0% of Lys. Experimental diets were formulated to ensure that Lys was the second limiting amino acid throughout the experiments. Initially, linear mixed models were fitted to data from each experiment. Then, data from the two experiments were combined to estimate dose-responses using a broken-line linear ascending (BLL) model, broken-line quadratic ascending (BLQ) model, or quadratic polynomial (QP). Model fit was compared using Bayesian information criterion (BIC). In experiment 1, ADG increased linearly (P = 0.009) with increasing SID Val:Lys with no apparent significant impact on G:F. In experiment 2, ADG and ADFI increased in a quadratic manner (P < 0.002) with increasing SID Val:Lys whereas G:F increased linearly (P < 0.001). Overall, the best-fitting model for ADG was a QP, whereby the maximum mean ADG was estimated at a 73.0% (95% CI: [69.5, >78.0%]) SID Val:Lys. For G:F, the overall best-fitting model was a QP with maximum estimated mean G:F at 69.0% (95% CI: [64.0, >78.0]) SID Val:Lys ratio. However, 99% of the maximum mean performance for ADG and G:F were achieved at, 68% and 63% SID Val:Lys ratio, respectively. Therefore, the SID Val:Lys requirement ranged from73.0% for maximum ADG to 63.2% SID Val:Lys to achieve 99% of maximum G:F in 25- to 45-kg BW pigs.

摘要

进行了两项实验，以在商业条件下估计 25-45kg 猪对标准化回肠可消化缬氨酸：赖氨酸（SID Val：Lys）剂量反应的影响。在实验 1 中，总共使用了 1134 头后备母猪（ PIC 337 × 1050），初始体重为 31.2kg ± 2.0kg（平均值 ± SD），进行了 19 天的生长试验，每个猪圈 27 头猪，每个处理 7 个猪圈。在实验 2 中，总共使用了 2100 头后备母猪（ PIC 327 × 1050），初始体重为 25.4 ± 1.9kg BW，进行了 22 天的生长试验，每个猪圈 25 头猪，每个处理 12 个猪圈。处理按初始 BW 进行随机完全块设计分组。在实验 1 中，共有 6 种 SID Val 为 59.0、62.5、65.9、69.6、73.0 和 75.5%的赖氨酸的饮食处理，在实验 2 中，共有 7 种 SID Val 为 57.0、60.6、63.9、67.5、69.6、69.6 和 75.5%的赖氨酸的饮食处理。实验日粮的设计确保了在整个实验中赖氨酸是第二限制氨基酸。最初，对每个实验的数据进行线性混合模型拟合。然后，将两个实验的数据合并，使用折线线性上升（BLL）模型、折线二次上升（BLQ）模型或二次多项式（QP）来估计剂量反应。使用贝叶斯信息准则（BIC）比较模型拟合情况。在实验 1 中，ADG 线性增加（P=0.009），SID Val：Lys 增加，而 G：F 没有明显的显著影响。在实验 2 中，ADG 和 ADFI 呈二次增加（P<0.002），而 G：F 呈线性增加（P<0.001）。总体而言，ADG 的最佳拟合模型是 QP，其中最大平均 ADG 估计为 73.0%（95%CI：[69.5，>78.0%]）SID Val：Lys。对于 G：F，整体最佳拟合模型是 QP，最大估计平均 G：F 为 69.0%（95%CI：[64.0，>78.0]）SID Val：Lys 比值。然而，ADG 和 G：F 的最大平均性能的 99%是在 SID Val：Lys 比值分别为 68%和 63%时达到的。因此，25-45kg BW 猪对 SID Val：Lys 的需求范围为 73.0%，以获得最大 ADG，至 63.2% SID Val：Lys，以获得最大 G：F 的 99%。