Chae Byungho, Poaty Ditengou Junior Isaac Celestin, Lee A-Leum, Tak Jisoo, Cheon Inhyeok, Choi Nag-Jin
Department of Animal Science, Jeonbuk National University, Jeonju 54896, Republic of Korea.
CJ Cheiljedang, Seoul 04560, Republic of Korea.
Animals (Basel). 2024 Oct 7;14(19):2884. doi: 10.3390/ani14192884.
Currently, the NRC amino acid (AA) requirements for pigs published in 2012 are used as a reference in variable swine industries. However, recent results in several articles suggest that the standardized ileal digestible (SID) AA-lysine (Lys) ratio significantly evolved over the last two decades, while some publications report inconsistent outcomes. Therefore, the present study used a meta-regression analysis to assess the relative ratio to lysine to maximize the feed efficiency of four essential amino acids (tryptophan, valine, isoleucine, and methionine) in pig diets. According to the PRISMA guidelines, articles examining the target AA requirement using a basal diet supplemented with varying levels of crystalline AA (tryptophan, valine, isoleucine, or methionine) were identified across Scopus, PubMed, and Science Direct. As a result, 23, 22, 16, and 9 articles using tryptophan, valine, isoleucine, and methionine were selected and categorized into experiments for inclusion in our meta-analysis. The results suggested that the requirements of tryptophan, valine, isoleucine, and methionine in our meta-regression analysis were superior to NRC recommendations, regardless of the regression models and the growth phases with significant RSQ values (RSQ ≈ 1). Also, the QUAD and CLP regression models emphasized higher requirements than the LP model for the great majority of amino acids and growth phases. The results of the QUAD and CLP models were selected as estimations of the amino acid requirements for pigs under challenged conditions, whereas the LP model was chosen to estimate the amino acid requirements of genetically improved pigs under a modern housing system. The results of this meta-regression analysis could be used to refresh the information on the NRC amino acids (AA) requirements for swine.
目前，2012年发布的美国国家研究委员会（NRC）猪氨基酸（AA）需求量被不同的养猪行业用作参考。然而，最近几篇文章的结果表明，在过去二十年中，标准化回肠可消化（SID）氨基酸与赖氨酸（Lys）的比例发生了显著变化，而一些出版物报道的结果并不一致。因此，本研究采用元回归分析来评估与赖氨酸的相对比例，以最大限度地提高猪日粮中四种必需氨基酸（色氨酸、缬氨酸、异亮氨酸和蛋氨酸）的饲料效率。根据系统评价和Meta分析的首选报告项目（PRISMA）指南，在Scopus、PubMed和Science Direct数据库中检索了使用添加不同水平结晶氨基酸（色氨酸、缬氨酸、异亮氨酸或蛋氨酸）的基础日粮来研究目标氨基酸需求量的文章。结果，分别筛选出了23篇、22篇、16篇和9篇使用色氨酸、缬氨酸、异亮氨酸和蛋氨酸的文章，并将其分类为纳入我们元分析的实验。结果表明，无论回归模型和生长阶段如何，我们的元回归分析中色氨酸、缬氨酸、异亮氨酸和蛋氨酸的需求量均优于NRC的建议值，且决定系数（RSQ）值显著（RSQ≈1）。此外，对于绝大多数氨基酸和生长阶段，二次（QUAD）回归模型和立方（CLP）回归模型强调的需求量高于线性规划（LP）模型。QUAD和CLP模型的结果被选为挑战条件下猪氨基酸需求量的估计值，而LP模型则被选择用于估计现代饲养系统下遗传改良猪的氨基酸需求量。该元回归分析的结果可用于更新NRC猪氨基酸需求量的信息。
