Department of Clinical and Biological Sciences, University of Torino, Torino, Italy.
Department of Nephrology, Centre Hospitalier Le Mans, Le Mans, France.
Nephrol Dial Transplant. 2018 Feb 1;33(2):189-193. doi: 10.1093/ndt/gfx358.
Chronic kidney disease (CKD) affects ∼10% of the world's adult population: it is one of the top 20 causes of death worldwide and its impact on patients and their families can be devastating. World Kidney Day and International Women's Day coincide in 2018, thus offering an opportunity to reflect on the importance of women's health, and specifically their kidney health, on the community and the next generations, as well as to strive to be more curious about the unique aspects of kidney disease in women so that we may apply these learnings more broadly. Girls and women, who make up ∼50% of the world's population, are important contributors to society and their families. Gender differences continue to exist around the world in access to education, medical care and participation in clinical studies. Pregnancy is a unique state for women, offering an opportunity for the diagnosis of kidney disease, and also a state where acute and chronic kidney diseases may manifest and that may impact future generations with respect to kidney health. There are various autoimmune and other conditions that are more likely to impact women with profound consequences for childbearing and on the fetus. Women have different complications on dialysis than men and are more likely to be donors than recipients of kidney transplants. In this editorial we focus on what we do and do not know about women, kidney health and kidney disease and what we might learn in the future to improve outcomes worldwide.
慢性肾脏病（CKD）影响着全球约 10%的成年人：它是全球前 20 大死因之一，对患者及其家庭的影响可能是毁灭性的。2018 年世界肾脏病日与国际妇女节恰逢其时，因此我们有机会反思妇女健康的重要性，特别是她们的肾脏健康对社区和子孙后代的重要性，以及努力更加关注妇女肾脏疾病的独特方面，以便我们能够更广泛地应用这些知识。占世界人口约 50%的女孩和妇女是社会和家庭的重要贡献者。在获得教育、医疗保健和参与临床研究方面，全球各地的性别差异仍然存在。怀孕是女性特有的一种状态，为诊断肾脏疾病提供了机会，也是急性和慢性肾脏病可能表现出来的一种状态，可能会对后代的肾脏健康产生影响。还有各种自身免疫性疾病和其他疾病更有可能对女性产生影响，对生育和胎儿产生深远的影响。女性在透析时的并发症与男性不同，她们更有可能成为肾脏移植的供体，而不是受体。在这篇社论中，我们重点关注我们对女性、肾脏健康和肾脏疾病的了解和不了解，以及我们未来可能会学到什么，以改善全球的治疗结果。
