Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø 9037, Norway.
Department of Neonatology and Perinatology, Northern State Medical University, 51 Troitsky Ave., Arkhangelsk 163000, Russia.
Int J Environ Res Public Health. 2018 Feb 3;15(2):261. doi: 10.3390/ijerph15020261.
This study aimed to assess whether adolescents have an increased risk of adverse pregnancy outcomes (APO) compared to adult women. We used data on 43,327 births from the population-based Arkhangelsk County Birth Registry, Northwest Russia, for 2012-2014. The perinatal outcomes included stillbirth, preterm birth (<37 and <32 weeks), low and very low birthweight, 5 min Apgar score <7 and <4, perinatal infections, and the need for neonatal transfer to a higher-level hospital. Multivariable logistic regression was applied to assess the associations between age and APO. Altogether, 4.7% of deliveries occurred in adolescents. Both folic acid intake and multivitamin intake during pregnancy were more prevalent in adults. Adolescents were more likely to be underweight, to smoke, and to have infections of the kidney and the genital tract compared to adult women. Compared to adults, adolescents were at lower risk of low birthweight, a 5 min Apgar score <7, and need for neonatal transfer. Adolescents had no increased risk of other APO studied in the adjusted analysis, suggesting that a constellation of other factors, but not young age per se, is associated with APO in the study setting.
本研究旨在评估与成年女性相比，青少年是否具有更高的不良妊娠结局（APO）风险。我们使用了 2012 年至 2014 年期间基于人群的俄罗斯西北部阿尔汉格尔斯克县出生登记处的 43327 例出生数据。围产期结局包括死胎、早产（<37 周和<32 周）、低出生体重和极低出生体重、5 分钟 Apgar 评分<7 和<4、围产期感染以及需要将新生儿转至更高一级医院。多变量逻辑回归用于评估年龄与 APO 之间的关联。总共，4.7%的分娩发生在青少年中。青少年和成年女性在怀孕期间叶酸和多种维生素的摄入量都更为普遍。与成年女性相比，青少年更可能体重不足、吸烟，并且更容易发生肾脏和生殖道感染。与成年女性相比，青少年发生低出生体重、5 分钟 Apgar 评分<7 和需要新生儿转院的风险较低。在调整分析中，青少年没有其他 APO 风险增加的迹象，这表明在研究环境中，与 APO 相关的是一系列其他因素，而不是单纯的年轻。
