Hah Young Min, Kim Sang Hoon, Jung Junyang, Kim Sung Su, Byun Jae Yong, Park Moon Suh, Yeo Seung Geun
Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
Department of Anatomy, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Auris Nasus Larynx. 2018 Oct;45(5):966-970. doi: 10.1016/j.anl.2018.01.007. Epub 2018 Feb 3.
This study was designed to evaluate the prognostic value of the blink reflex (BR) test in patients with Bell's palsy (BP) or Ramsay Hunt syndrome (RHS).
The House-Brackmann (HB) grade of patients diagnosed with BP and RHS was determined at first visit and 3 months later. Final HB grade III-VI was defined as an incomplete recovery. Factors evaluated as prognostic of poor recovery included electroneurography (ENoG) degeneration rate (DR)>90%, and absence of BR. Rates of complete and incomplete recovery were calculated and the associations between prognostic factors and recovery were determined.
Of the 129 included patients, 98 (76%) had BP and 31 (24%) had RHS. Absence of BR and low mean ENoG value were significantly associated with incomplete recovery in both the BP and RHS groups (p<0.05 each). Initial HB grade V-VI was significantly associated with rate of incomplete recovery in patients with RHS (p<0.05 each). Severe residual palsy (final HB grade V-VI) in the absence of BR was significantly more frequent in patients with RHS than with BP (p<0.05).
BR test results were a good prognostic indicator in patients with BP and RHS, as were ENoG value. Absence of BR was more frequently associated with severe residual palsy in RHS than in BP.
本研究旨在评估眨眼反射(BR)测试对贝尔麻痹(BP)或拉姆齐·亨特综合征(RHS)患者的预后价值。
对诊断为BP和RHS的患者,在初诊时及3个月后确定其House-Brackmann(HB)分级。最终HB分级为III-VI级被定义为恢复不完全。评估为恢复不佳预后的因素包括神经电图(ENoG)退变率(DR)>90%以及无BR。计算完全恢复和不完全恢复的比率,并确定预后因素与恢复之间的关联。
在纳入的129例患者中,98例(76%)患有BP,31例(24%)患有RHS。BP组和RHS组中,无BR和ENoG平均低值均与恢复不完全显著相关(均p<0.05)。初始HB分级为V-VI级与RHS患者的不完全恢复率显著相关(均p<0.05)。在无BR的情况下,RHS患者出现严重残留麻痹(最终HB分级为V-VI级)的情况比BP患者更常见(p<0.05)。
BR测试结果以及ENoG值都是BP和RHS患者良好的预后指标。与BP相比,RHS中无BR更常与严重残留麻痹相关。