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细胞外基质移植物在翼状胬肉手术中的实验应用。

Experimental use of an extracellular matrix graft in pterygium surgery.

作者信息

Anderson Erik W, Dwarakanathan Suri, Haddadin Ramez

机构信息

Wake Forest Baptist Medical Center, Winston Salem, North Carolina.

John H. Stroger, Jr. Hospital of Cook County, Chicago Illinois.

出版信息

Digit J Ophthalmol. 2017 Dec 28;23(4):15-17. doi: 10.5693/djo.02.2017.11.001. eCollection 2017.

Abstract

A 40-year-old man presented with a primary pterygium of the right eye and underwent pterygium excision using mitomycin C and placement of an extracellular matrix (ECM) adjuvant. As an adjuvant in pterygium surgery, ECM serves as a scaffold while promoting the growth of normal conjunctiva. Perioperatively, the ECM graft was found to be easily manipulated on the surgical field. It attached to the scleral bed with fibrin glue without complication. Postoperatively, there was no inflammation or local tissue reaction to the porcine ECM graft. At the most recent follow-up examination, 6 months postoperatively, there were no signs of recurrence of the pterygium past the limbus. This is the first report describing the use of ECM as an adjuvant to pterygium excision.

摘要

一名40岁男性因右眼原发性翼状胬肉就诊,接受了使用丝裂霉素C的翼状胬肉切除术并放置了细胞外基质(ECM)佐剂。作为翼状胬肉手术的佐剂,ECM在促进正常结膜生长的同时充当支架。围手术期,发现ECM移植物在手术视野中易于操作。它用纤维蛋白胶附着在巩膜床上,无并发症。术后,对猪ECM移植物无炎症或局部组织反应。在术后6个月的最近一次随访检查中,角膜缘外无翼状胬肉复发迹象。这是第一篇描述使用ECM作为翼状胬肉切除术佐剂的报告。

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Experimental use of an extracellular matrix graft in pterygium surgery.细胞外基质移植物在翼状胬肉手术中的实验应用。
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