Karamanlı Harun, Kayhan Fatih, Akgedik Recep
Department of Pulmonology, Atatürk Chest Diseases and Chest Surgery Training and Research Hospital, Ankara, Turkey.
Department of Psychiatry, Selcuk University Faculty of Medicine, Konya, Turkey.
Turk Thorac J. 2016 Jul;17(3):109-113. doi: 10.5578/ttj.30506. Epub 2016 Jul 1.
Different studies have investigate depressive symptom degree within sleep disordered patients with obstructive sleep apnea (OSA). However, little is known and unclear about OSA in patients with depression symptom in the literature. The purpose of this study was to investigate patients with OSA would have a higher prevalence of depression symptom relative to control patients.
72 patients with OSA (AHI ≥ 5) and 24 control subjects (AHI < 5) were assessed for depression symptom using the Beck Depression Inventory. Participants were underwent an overnight polysomnography assessment. An apnea-hypopnea index ≥ 5 events per hour was used as diagnosis for OSA. The associations between each total score on the Beck Depressive Inventory (BDI) and polysomnographic parameters were examined by correlation analysis.
We demonstrated that BDI scores has statistically significant correlation with the OSA in our present study according to similar previous studies (p= 0.008). Oxygen Desaturation Index (ODI) has correlated with BDI (r= 0.31).
These findings show that the frequency depression symptom is higher among individuals with OSA. Patients with OSA should be screened cautiously for depressive disorders.
不同研究已对阻塞性睡眠呼吸暂停（OSA）睡眠障碍患者的抑郁症状程度进行了调查。然而，文献中关于抑郁症状患者的OSA情况鲜为人知且尚不明确。本研究的目的是调查与对照患者相比，OSA患者抑郁症状的患病率是否更高。
使用贝克抑郁量表对72例OSA患者（呼吸暂停低通气指数[AHI]≥5）和24例对照受试者（AHI<5）进行抑郁症状评估。参与者接受了整夜多导睡眠图评估。每小时呼吸暂停低通气指数≥5次事件被用作OSA的诊断标准。通过相关性分析检查贝克抑郁量表（BDI）各总分与多导睡眠图参数之间的关联。
根据以往类似研究，我们在本研究中证明BDI评分与OSA具有统计学显著相关性（p=0.008）。氧去饱和指数（ODI）与BDI相关（r=0.31）。
这些发现表明，OSA个体中抑郁症状的发生率更高。应对OSA患者进行抑郁障碍的谨慎筛查。
