Song Hannah, Morley Keith W, Trowbridge Ryan M, Butler Daniel C, Liang Marilyn G, Gellis Stephen E, Huang Jennifer T
Harvard Medical School, Boston, MA, USA.
Dermatology Program, Boston Children's Hospital, Boston, MA, USA.
Pediatr Dermatol. 2018 Mar;35(2):230-233. doi: 10.1111/pde.13415. Epub 2018 Feb 6.
In this case series, we report seven immunized healthy children without underlying immunodeficiency who presented with herpes zoster that correlated with varicella-zoster vaccination site. The morphology of the lesions included erythematous papules, pseudovesicles, and plaques, with associated pain in two and pruritus in three patients; systemic symptoms ranged from none to low-grade fevers, upper respiratory symptoms, and joint pain. These cases highlight the clinical, diagnostic, and therapeutic implications of herpes zoster in vaccinated children.
在本病例系列中,我们报告了7名无潜在免疫缺陷的健康儿童,他们接种疫苗后出现带状疱疹,且与水痘-带状疱疹疫苗接种部位相关。皮损形态包括红斑丘疹、假性水疱和斑块,2例伴有疼痛,3例伴有瘙痒;全身症状从无到低热、上呼吸道症状和关节痛不等。这些病例凸显了接种疫苗儿童发生带状疱疹的临床、诊断和治疗意义。