National Immunisation Programme Department, Chinese Center for Disease Control and Prevention, Beijing, China.
State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
J Infect. 2018 May;76(5):429-437. doi: 10.1016/j.jinf.2018.01.007. Epub 2018 Feb 12.
The Global Meningococcal Initiative (GMI) is a global expert group, including scientists, clinicians and public health officials from a wide range of specialities. The goal of the GMI is to prevent meningococcal disease worldwide through education, research, and co-operation. The Chinese GMI roundtable meeting was held in June 2017. The GMI met with local experts to gain insight into the meningococcal disease burden in China and current prevention and vaccination strategies in place. China experienced five epidemics of serogroup A meningococcal disease (MenA) between 1938 and 1977, with peak incidence of 403/100,000 recorded in 1967. MenA incidence rates have significantly declined following the universal introduction of the MenA polysaccharide vaccine in China in the 1980s. Further, surveillance data indicates changing meningococcal epidemiology in China with the emergence of new clones of serogroup B from serogroup C clonal complex (cc) 4821 due to capsular switching, and the international spread of serogroup W cc11. The importance of carriage and herd protection for controlling meningococcal disease was highlighted with the view to introduce conjugate vaccines and serogroup B vaccines into the national immunization schedule. Improved disease surveillance and standardized laboratory techniques across and within provinces will ensure optimal epidemiological monitoring.
全球脑膜炎球菌倡议组织（GMI）是一个全球性专家组，成员包括来自广泛专业领域的科学家、临床医生和公共卫生官员。GMI 的目标是通过教育、研究和合作，在全球范围内预防脑膜炎球菌病。2017 年 6 月，中国举行了 GMI 圆桌会议。GMI 与当地专家会面，深入了解中国脑膜炎球菌病负担以及目前的预防和疫苗接种策略。中国在 1938 年至 1977 年期间经历了五波 A 群脑膜炎球菌病（MenA）流行，1967 年的发病率峰值为 403/100,000。自 20 世纪 80 年代在中国普遍引入 A 群脑膜炎球菌多糖疫苗以来，MenA 的发病率已显著下降。此外，监测数据表明，由于荚膜转换，新的 B 群克隆从 C 群克隆复合体（cc）4821 出现，以及 W 群 cc11 在国际上的传播，中国脑膜炎球菌病的流行病学正在发生变化。鉴于此，专家组强调了带菌者和群体保护在控制脑膜炎球菌病方面的重要性，以期将结合疫苗和 B 群疫苗引入国家免疫计划。加强省际和省内的疾病监测和标准化实验室技术，将确保最佳的流行病学监测。
