• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

访问双环[4.2.0]辛烯单体以探索交替开环复分解聚合的范围。

Access to Bicyclo[4.2.0]octene Monomers To Explore the Scope of Alternating Ring-Opening Metathesis Polymerization.

机构信息

Department of Chemistry, Stony Brook University , Stony Brook, New York 11794-3400, United States.

出版信息

J Org Chem. 2018 Mar 2;83(5):2892-2897. doi: 10.1021/acs.joc.8b00054. Epub 2018 Feb 14.

DOI:10.1021/acs.joc.8b00054
PMID:29406722
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5838619/
Abstract

Bicyclo[4.2.0]oct-1(8)-ene-8-carboxamides undergo alternating ring-opening metathesis polymerization (AROMP) with cyclohexene. Herein, a general method for the preparation of bicyclo[4.2.0]oct-(8)-ene-8-carboxy derivatives is described. The central 8-cyano intermediate provides entry to five different functional group substituents on the alkene. These monomers were tested as potential substrates for AROMP with cyclohexene. In addition to the carboxamide, the carboxynitrile and carboxaldehyde are also substrates for AROMP. In the case of the carboxaldehyde, the polymer is regioregular. However, the addition of carboxynitrile is stereoirregular and slow.

摘要

双环[4.2.0]辛-1(8)-烯-8-甲酰胺与环已烯进行交替开环复分解聚合（AROMP）。本文描述了一种制备双环[4.2.0]辛-（8）-烯-8-羧酸衍生物的通用方法。中间的 8-氰基中间体为烯烃上的 5 种不同官能团取代基提供了入口。这些单体被测试为与环已烯进行 AROMP 的潜在底物。除了酰胺外，氰基羧酸和醛也是 AROMP 的底物。对于醛，聚合物是区域规整的。然而，氰基羧酸的加成是立体不规则且缓慢的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8073/5838619/c77d5b2a268b/jo-2018-000544_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8073/5838619/4cb7710de3d6/jo-2018-000544_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8073/5838619/661265d37fff/jo-2018-000544_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8073/5838619/77f9d0207fd1/jo-2018-000544_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8073/5838619/c77d5b2a268b/jo-2018-000544_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8073/5838619/4cb7710de3d6/jo-2018-000544_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8073/5838619/661265d37fff/jo-2018-000544_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8073/5838619/77f9d0207fd1/jo-2018-000544_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8073/5838619/c77d5b2a268b/jo-2018-000544_0001.jpg

相似文献

1
Access to Bicyclo[4.2.0]octene Monomers To Explore the Scope of Alternating Ring-Opening Metathesis Polymerization.访问双环[4.2.0]辛烯单体以探索交替开环复分解聚合的范围。
J Org Chem. 2018 Mar 2;83(5):2892-2897. doi: 10.1021/acs.joc.8b00054. Epub 2018 Feb 14.
2
Precision Synthesis of Alternating Copolymers via Ring-Opening Polymerization of 1-Substituted Cyclobutenes.通过1-取代环丁烯的开环聚合精确合成交替共聚物
Acc Chem Res. 2016 Mar 15;49(3):408-17. doi: 10.1021/acs.accounts.5b00490. Epub 2016 Feb 25.
3
Long-Range Kinetic Effects on the Alternating Ring Opening Metathesis of Bicyclo[4.2.0]oct-6-ene-7-carboxamides and Cyclohexene.双环[4.2.0]辛-6-烯-7-甲酰胺和环己烯的交替开环复分解反应的远程动力学效应
ACS Org Inorg Au. 2023 May 30;3(4):233-240. doi: 10.1021/acsorginorgau.3c00013. eCollection 2023 Aug 2.
4
Alternating Ring-Opening Metathesis Polymerization (AROMP) of Hydrophobic and Hydrophilic Monomers Provides Oligomers with Side-Chain Sequence Control.疏水性和亲水性单体的交替开环易位聚合（AROMP）可实现对低聚物侧链序列的控制。
Macromolecules. 2018 Jun 12;51(11):3932-3940. doi: 10.1021/acs.macromol.8b00562. Epub 2018 May 15.
5
A Bicyclo[4.2.0]octene-Derived Monomer Provides Completely Linear Alternating Copolymers via Alternating Ring-Opening Metathesis Polymerization (AROMP).一种双环[4.2.0]辛烯衍生单体通过交替开环易位聚合（AROMP）提供完全线性的交替共聚物。
Macromolecules. 2014 Oct 14;47(19):6572-6579. doi: 10.1021/ma5012039. Epub 2014 Sep 23.
6
Incorporation of Large Cycloalkene Rings into Alternating Copolymers Allows Control of Glass Transition and Hydrophobicity.将大环烯烃环并入交替共聚物可实现对玻璃化转变和疏水性的控制。
ACS Macro Lett. 2018 Sep 18;7(9):1068-1072. doi: 10.1021/acsmacrolett.8b00510. Epub 2018 Aug 16.
7
Gradient Copolymer Prepared from Alternating Ring-Opening Metathesis of Three Monomers.由三种单体的交替开环易位聚合制备的梯度共聚物。
Polym Chem. 2021 Oct 21;12(39):5613-5622. doi: 10.1039/d1py00690h. Epub 2021 Sep 13.
8
Ru-Catalyzed Isomerization Provides Access to Alternating Copolymers via Ring-Opening Metathesis Polymerization.钌催化的异构化反应通过开环易位聚合反应实现交替共聚物的合成。
Macromolecules. 2015 Jul 28;48(14):4793-4800. doi: 10.1021/acs.macromol.5b01058. Epub 2015 Jul 7.
9
Efficient entry to the [2.2.2]-diazabicyclic ring system via diastereoselective domino reaction sequence.通过非对映选择性多米诺反应序列高效进入[2.2.2]-二氮杂双环环系统。
Org Lett. 2012 May 18;14(10):2458-61. doi: 10.1021/ol3007056. Epub 2012 May 9.
10
Sequential N-acylamide methylenation-enamide ring-closing metathesis: construction of benzo-fused nitrogen heterocycles.顺序N-酰基酰胺亚甲基化-烯酰胺闭环复分解反应：苯并稠合氮杂环的构建
J Org Chem. 2006 Sep 1;71(18):7028-34. doi: 10.1021/jo061180j.

引用本文的文献

1
Glycopolymers Prepared by Alternating Ring-Opening Metathesis Polymerization Provide Access to Distinct, Multivalent Structures for the Probing of Biological Activity.通过交替开环易位聚合制备的糖聚合物可提供独特的多价结构，用于探究生物活性。
ACS Bio Med Chem Au. 2024 May 28;4(4):214-225. doi: 10.1021/acsbiomedchemau.4c00018. eCollection 2024 Aug 21.
2
Cascade Alternating Metathesis Cyclopolymerization of Diynes and Dihydrofuran.二炔与二氢呋喃的级联交替复分解环聚合反应。
ACS Macro Lett. 2022 May 17;11(5):630-635. doi: 10.1021/acsmacrolett.2c00140. Epub 2022 Apr 18.
3
Substituent Effects Provide Access to Tetrasubstituted Ring-Opening Olefin Metathesis of Bicyclo[4.2.0]oct-6-enes.

本文引用的文献

1
Synthesis of cis,syndiotactic-A-alt-B Copolymers from Enantiomerically Pure Endo-2-Substituted-5,6-Norbornenes.由对映体纯的内-2-取代-5,6-降冰片烯合成顺式、间同立构的A-alt-B共聚物。
J Am Chem Soc. 2017 Apr 12;139(14):5043-5046. doi: 10.1021/jacs.7b01747. Epub 2017 Mar 31.
2
Control of Grafting Density and Distribution in Graft Polymers by Living Ring-Opening Metathesis Copolymerization.通过活性开环复分解共聚控制接枝聚合物中的接枝密度和分布。
J Am Chem Soc. 2017 Mar 15;139(10):3896-3903. doi: 10.1021/jacs.7b00791. Epub 2017 Mar 3.
3
Synthesis of , A-B Copolymers from Two Enantiomerically Pure -2,3-Disubstituted-5,6-Norbornenes.
取代基效应为双环[4.2.0]辛-6-烯的四取代开环烯烃复分解反应提供了途径。
ACS Org Inorg Au. 2021 Oct 6;1(1):29-36. doi: 10.1021/acsorginorgau.1c00016. Epub 2021 Aug 13.
4
Alternating Ring-Opening Metathesis Polymerization Provides Easy Access to Functional and Fully Degradable Polymers.交替开环易位聚合反应为合成功能性且可完全降解的聚合物提供了便捷途径。
Macromolecules. 2020 Jul 28;53(14):5857-5868. doi: 10.1021/acs.macromol.0c01051. Epub 2020 Jul 16.
5
Cationic Amphiphilic Alternating Copolymers with Tunable Morphology.具有可调形态的阳离子两亲性交替共聚物
Polym Chem. 2020 Sep 14;11(34):5424-5430. doi: 10.1039/d0py00782j. Epub 2020 Jul 29.
6
Alternating Cascade Metathesis Polymerization of Enynes and Cyclic Enol Ethers with Active Ruthenium Fischer Carbenes.交替级联烯炔和环状烯醇醚与活性钌费歇尔卡宾的聚合反应。
J Am Chem Soc. 2020 Jul 29;142(30):12942-12947. doi: 10.1021/jacs.0c06045. Epub 2020 Jul 20.
7
Alternating Ring-Opening Metathesis Polymerization (AROMP) of Hydrophobic and Hydrophilic Monomers Provides Oligomers with Side-Chain Sequence Control.疏水性和亲水性单体的交替开环易位聚合（AROMP）可实现对低聚物侧链序列的控制。
Macromolecules. 2018 Jun 12;51(11):3932-3940. doi: 10.1021/acs.macromol.8b00562. Epub 2018 May 15.
8
Incorporation of Large Cycloalkene Rings into Alternating Copolymers Allows Control of Glass Transition and Hydrophobicity.将大环烯烃环并入交替共聚物可实现对玻璃化转变和疏水性的控制。
ACS Macro Lett. 2018 Sep 18;7(9):1068-1072. doi: 10.1021/acsmacrolett.8b00510. Epub 2018 Aug 16.
由两种对映体纯的-2,3-二取代-5,6-降冰片烯合成A-B共聚物。
ACS Cent Sci. 2016 Sep 28;2(9):631-636. doi: 10.1021/acscentsci.6b00200. Epub 2016 Sep 6.
4
Designing Sequence Selectivity into a Ring-Opening Metathesis Polymerization Catalyst.设计开环复分解聚合催化剂的序列选择性。
Acc Chem Res. 2016 May 17;49(5):1052-60. doi: 10.1021/acs.accounts.6b00085. Epub 2016 Apr 22.
5
Precision Synthesis of Alternating Copolymers via Ring-Opening Polymerization of 1-Substituted Cyclobutenes.通过1-取代环丁烯的开环聚合精确合成交替共聚物
Acc Chem Res. 2016 Mar 15;49(3):408-17. doi: 10.1021/acs.accounts.5b00490. Epub 2016 Feb 25.
6
Catalysts for CO2/epoxide ring-opening copolymerization.用于二氧化碳/环氧化物开环共聚的催化剂。
Philos Trans A Math Phys Eng Sci. 2016 Feb 28;374(2061). doi: 10.1098/rsta.2015.0085.
7
Transformation of Step-Growth Polymerization into Living Chain-Growth Polymerization.逐步增长聚合向活性链增长聚合的转变。
Chem Rev. 2016 Feb 24;116(4):1950-68. doi: 10.1021/acs.chemrev.5b00393. Epub 2015 Nov 10.
8
Ru-Catalyzed Isomerization Provides Access to Alternating Copolymers via Ring-Opening Metathesis Polymerization.钌催化的异构化反应通过开环易位聚合反应实现交替共聚物的合成。
Macromolecules. 2015 Jul 28;48(14):4793-4800. doi: 10.1021/acs.macromol.5b01058. Epub 2015 Jul 7.
9
Multiple Olefin Metathesis Polymerization That Combines All Three Olefin Metathesis Transformations: Ring-Opening, Ring-Closing, and Cross Metathesis.多种烯烃复分解聚合反应，结合了三种烯烃复分解反应：开环、闭环和交叉复分解。
J Am Chem Soc. 2015 Jul 29;137(29):9262-5. doi: 10.1021/jacs.5b06033. Epub 2015 Jul 17.
10
Living Alternating Ring-Opening Metathesis Polymerization Based on Single Monomer Additions.基于单体逐一添加的交替共聚开环易位聚合反应。
J Am Chem Soc. 2015 Aug 12;137(31):9922-6. doi: 10.1021/jacs.5b05497. Epub 2015 Jul 30.