The Ottawa Hospital Research Institute, 501 Smyth Rd., Ottawa, ON K1H 8L6, Canada; The Department of Medicine, The Ottawa Hospital, General Campus, 501 Smyth Rd., Ottawa, ON K1H 8L6, Canada; University of Ottawa, 451 Smyth Rd, Ottawa, ON K1H 8M5, Canada; International Network of Venous Thromboembolism Clinical Research Networks (INVENT), Canada.
The Ottawa Hospital Research Institute, 501 Smyth Rd., Ottawa, ON K1H 8L6, Canada; International Network of Venous Thromboembolism Clinical Research Networks (INVENT), Canada.
Thromb Res. 2018 Mar;163:128-131. doi: 10.1016/j.thromres.2018.01.050. Epub 2018 Jan 31.
Venous thromboembolism (VTE) represents a major global burden of disease and requires collaborative efforts to conduct large, high-quality investigator-initiated and academically sponsored studies addressing the most relevant clinical questions. Owing to increasing regulatory requirements, the highly competitive nature of peer-reviewed funding and costs associated with conducting large, multinational clinical trials, completing practice-changing research constitutes a growing challenge for clinical investigators. As clinical trialists interested in VTE, we founded INVENT (International Network of Venous Thromboembolism Clinical Research Networks) in an effort to promote and accelerate patient-oriented, investigator-initiated, international collaborative research, to identify, prioritize and answer key clinical research questions for patients with VTE. We report on our activities to formalize the INVENT network and our accomplishments in our first year.
静脉血栓栓塞症（VTE）是全球重大疾病负担之一，需要协同努力开展大型高质量的由研究者发起和学术机构赞助的研究，以解决最相关的临床问题。由于监管要求不断提高、同行评议资助的高度竞争性以及开展大型跨国临床试验相关成本的增加，完成改变实践的研究对临床研究者来说构成了越来越大的挑战。作为对 VTE 感兴趣的临床试验研究者，我们成立了 INVENT（静脉血栓栓塞症临床研究网络国际网络），努力促进和加速以患者为中心、由研究者发起的国际合作研究，以确定、优先考虑并回答 VTE 患者的关键临床研究问题。我们报告了我们为使 INVENT 网络正式化而开展的活动以及我们在第一年取得的成果。
