Goodman L J, Kaplan R L, Petrak R M, Fliegelman R M, Taff D, Walton F, Penner J L, Trenholme G M
Antimicrob Agents Chemother. 1986 Feb;29(2):185-7. doi: 10.1128/AAC.29.2.185.
Ciprofloxacin was compared with erythromycin for the eradication of Campylobacter species that were chronically excreted in the stools of marmosets (Saguinus labiatus labiatus, Saguinus fuscicollis nigrifrons, and Saguinus fuscicollis illigeri). Stool cultures were negative within 48 h of the beginning of treatment with either agent. Within 10 days after the end of therapy, however, Campylobacter species were again isolated from the stools of six animals that had received erythromycin. During an 8-week follow-up period, no animal that had received ciprofloxacin relapsed. High levels of ciprofloxacin in the stool (mean, 49.2 micrograms/g) possibly contributed to the efficacy of this agent.
将环丙沙星与红霉素进行比较，以根除狨猴（白唇狨、黑额绒猴和伊氏倭狨）粪便中长期排出的弯曲杆菌属细菌。使用任何一种药物治疗开始后48小时内，粪便培养均为阴性。然而，在治疗结束后的10天内，从接受红霉素治疗的6只动物的粪便中再次分离出弯曲杆菌属细菌。在8周的随访期内，接受环丙沙星治疗的动物均未复发。粪便中环丙沙星的高浓度（平均49.2微克/克）可能是该药物疗效的原因。
