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妇科肿瘤患者疼痛管理的持续策略和更新。

Ongoing strategies and updates on pain management in gynecologic oncology patients.

机构信息

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Michigan, Ann Arbor, MI, United States.

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Michigan, Ann Arbor, MI, United States.

出版信息

Gynecol Oncol. 2018 May;149(2):410-419. doi: 10.1016/j.ygyno.2018.01.034. Epub 2018 Mar 2.

Abstract

The opioid crisis in the United States has been declared a public health emergency. Various governmental agencies, cancer care organizations and the Centers for Disease Control and Prevention have issued guidelines in hopes of managing this crisis. Curbing over-prescription of opioids by medical professionals has been a central theme in many of these guidelines. Gynecologic oncologists encounter patients with a variety of pain sources, including acute pain secondary to the underlying malignancy or surgical procedures as well as chronic pain related to the malignancy and the sequelae of treatments rendered. In this review, we discuss the various etiologies of pain experienced by gynecologic oncology patients and discuss modalities frequently used to treat this pain. We highlight strategies to reduce the number of opioids prescribed and focus on incorporating non-opioid pain relief management principles in this review. We also discuss the mechanisms and etiology of various types of pain, with a focus on multimodal treatment strategies including preoperative counseling, strategies to identify individuals at risk of developing opioid dependence, and the role of symptom management and palliative care teams. Finally, we provide a blueprint for gynecologic oncology practices to develop their practice-specific pain management contracts to engage patients in a meaningful conversation around the addictive potential of opioids.

摘要

美国的阿片类药物危机已被宣布为公共卫生紧急事件。为了应对这一危机,各种政府机构、癌症护理组织和疾病控制与预防中心都发布了相关指南。其中的一个主要主题是遏制医疗专业人员过度开具阿片类药物。妇科肿瘤学家会遇到各种来源的疼痛患者,包括恶性肿瘤或手术引起的急性疼痛,以及与恶性肿瘤和治疗相关的后遗症引起的慢性疼痛。在这篇综述中,我们讨论了妇科肿瘤患者经历的各种疼痛病因,并讨论了常用于治疗这种疼痛的方法。我们强调了减少开具阿片类药物数量的策略,并重点介绍了在这篇综述中纳入非阿片类药物疼痛管理原则的方法。我们还讨论了各种类型疼痛的机制和病因,重点介绍了包括术前咨询在内的多模式治疗策略,以确定有发展为阿片类药物依赖风险的个体,以及症状管理和姑息治疗团队的作用。最后,我们为妇科肿瘤学实践提供了一个蓝图,以制定特定于实践的疼痛管理合同,让患者就阿片类药物的成瘾潜力进行有意义的对话。

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