Hofstetter Lorne W, Yeo Desmond T B, Dixon W Thomas, Marinelli Luca, Foo Thomas K
Department of Radiology, University of Utah, Salt Lake City, UT, USA.
GE Global Research, Niskayuna, NY, USA.
Magn Reson Imaging. 2018 Jun;49:86-93. doi: 10.1016/j.mri.2018.01.002. Epub 2018 Feb 2.
A three-point image reconstruction method for internally referenced MR thermometry was developed. The technique exploits the fact that temperature-induced changes in the water resonance frequency are small relative to the chemical shift difference between water and fat signals. This property enabled the use of small angle approximations to derive an analytic phase-based fat-water separation method for MR thermometry. Ethylene glycol and cream cool-down experiments were performed to validate measurement technique. Over a cool-down temperature range of 20 °C, maximum deviation between probe and MR measurement (averaged over 1.3 cm region surrounding probe) was 0.6 °C and 1.1 °C for ethylene glycol and cream samples, respectively.
开发了一种用于内部参考磁共振温度测量的三点图像重建方法。该技术利用了这样一个事实，即相对于水和脂肪信号之间的化学位移差异，温度引起的水共振频率变化较小。这一特性使得能够使用小角度近似来推导一种基于相位的用于磁共振温度测量的脂肪-水分离解析方法。进行了乙二醇和乳膏冷却实验以验证测量技术。在20℃的冷却温度范围内，对于乙二醇和乳膏样品，探头测量值与磁共振测量值之间的最大偏差（在探头周围1.3厘米区域内平均）分别为0.6℃和1.1℃。
