Yonkosky D M, Pochi P E
Dermatol Clin. 1986 Jan;4(1):127-36.
Acne vulgaris is a common skin disorder. Although it is most prevalent in the second decade of life, its beginnings are heralded by increased activity of the sebaceous glands and faulty follicular keratinization, which are already evident in mid to late childhood. The subsequent and increasing proliferation of the follicular anaerobic diphtheroid microflora contribute further as an important pathogenic factor in the generation of inflammatory lesions. Treatments of acne, therefore, are aimed at reducing the follicular anaerobic bacteria, counteracting the follicular hyperkeratosis, and inhibiting the activity of sebaceous glands.
寻常痤疮是一种常见的皮肤疾病。尽管它在人生的第二个十年最为普遍，但其发病始于皮脂腺活动增加和毛囊角化异常，这在儿童中期到晚期就已明显。随后毛囊厌氧类白喉菌群的不断增殖，作为炎症性损害发生的一个重要致病因素，进一步加重了病情。因此，痤疮的治疗旨在减少毛囊厌氧菌、对抗毛囊过度角化并抑制皮脂腺的活性。
