Buchweitz Augusto, Costa Adriana Corrêa, Toazza Rudineia, de Moraes Ana Bassôa, Cara Valentina Metsavaht, Esper Nathália Bianchini, Aguzzoli Cristiano, Gregolim Bruna, Dresch Luiz Fernando, Soldatelli Matheus Dorigatti, da Costa Jaderson Costa, Portuguez Mirna Wetters, Franco Alexandre Rosa
a School of Humanities, Brain Institute of Rio Grande do Sul (BRAINS) , Pontifical Catholic University of Rio Grande do Sul (PUCRS) , Porto Alegre , Brazil.
b Graduate School of Neurosciences, Basic Health Sciences Institute , Federal University of Rio Grande do Sul (UFRGS) , Porto Alegre , Brazil.
Dev Neuropsychol. 2019 Jan-Feb;44(1):146-157. doi: 10.1080/87565641.2017.1292516. Epub 2018 Feb 7.
The goal of the present study was to investigate intrinsic and reading-related brain function associated with dyslexia and typical readers in monolingual Brazilian children. Two fMRI studies were carried out: a resting-state and a word-reading study. The results show (a) underconnectivity between the occipitotemporal region (visual word form area) and the brain's default-mode network in dyslexic readers and (b) more activation of the anterior cingulate cortex for typical readers relative to dyslexic readers. The findings provide evidence for brain connectivity and function differences in an underrepresented population in fMRI studies of dyslexia; the results suggest atypical intrinsic function, and differences in directed attention processes in dyslexia.
本研究的目的是调查巴西单语儿童中与诵读困难及正常阅读者相关的内在和阅读相关脑功能。进行了两项功能磁共振成像（fMRI）研究：一项静息态研究和一项单词阅读研究。结果显示：（a）诵读困难读者的枕颞区（视觉词形区）与大脑默认模式网络之间连接不足；（b）与诵读困难读者相比，正常阅读者的前扣带回皮质激活更多。这些发现为诵读困难的fMRI研究中代表性不足人群的脑连接和功能差异提供了证据；结果表明诵读困难存在非典型的内在功能以及定向注意过程的差异。
