Teixeira Luiz Eduardo Moreira, Pádua Bruno Jannotti, Castilho André Moreira, Araújo Ivana Duval de, Andrade Marco Antônio Percope de, Cardoso Valbert Nascimento, Diniz Simone Odília, Leal Jefferson Soares, Takenaka Isabella Kuniko
PhD, Assistant Professor, Department of Locomotive Apparatus, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte-MG, Brazil. Conception and design of the study; acquisition, analysis and interpretation of data; manuscript writing; critical revision.
MD, Department of Orthopedics, UFMG, Belo Horizonte-MG, Brazil. Acquisition, analysis and interpretation of data.
Acta Cir Bras. 2018 Jan;33(1):14-21. doi: 10.1590/s0102-865020180010000002.
To compare the influence of two metallic implants in the diagnosis of periprosthetic infection using 99m technetium-labeled ceftizoxime.
Twenty rats were randomly divided into four groups, which received sterile and contaminated titanium and stainless steel implants. After 3 weeks, scintilographic images were obtained using a gamma chamber. Radioactivity counts were obtained for the region of interest (ROI) on the operated and non-operated paws.
Groups A, B, and C showed homogenous distribution of the radiopharmaceutical. Hyper uptake was observed in the operated paw from group D. The ROI target count was higher in the two groups with stainless steel implants. Among the control groups, the count was higher in the stainless steel group. Furthermore, among the contaminated groups, the uptake was higher in the stainless steel group, with a significant difference. The target: non-target ratio was significantly lower in the control and contaminated groups with both titanium and stainless steel, but the comparison between control groups and contaminated groups was only significant in the former. The cpm/g observed after a decay of 48h showed statistically significant differences between groups.
Different biomaterials used in implants have an influence on the results of scintigraphy with 99mTc-CFT.
比较两种金属植入物对使用99m锝标记头孢唑肟诊断假体周围感染的影响。
将20只大鼠随机分为四组，分别植入无菌和受污染的钛及不锈钢植入物。3周后，使用γ相机获得闪烁扫描图像。对手术侧和非手术侧爪子的感兴趣区域（ROI）进行放射性计数。
A、B和C组放射性药物分布均匀。D组手术侧爪子观察到放射性摄取增加。植入不锈钢的两组ROI目标计数较高。在对照组中，不锈钢组的计数较高。此外，在受污染组中，不锈钢组的摄取较高，差异有统计学意义。钛和不锈钢的对照组及受污染组的目标：非目标比值均显著较低，但对照组与受污染组之间的比较仅在前者中有显著差异。48小时衰变后观察到的每克每分钟计数在各组之间有统计学显著差异。
植入物中使用的不同生物材料对99mTc-CFT闪烁扫描结果有影响。
