Dourado Cláudia de Souza, Souza Camila Brandão de, Castro Denise Silveira de, Zandonade Eliana, Miotto Maria Helena Monteiro de Barros, Amorim Maria Helena Costa
Universidade Federal do Espírito Santo. Av. Marechal Campos 1468, Maruípe. 29000-000 Vitória ES Brasil. claudias_dourado@ hotmail.com.
Universidade Federal de São Paulo. São Paulo SP Brasil.
Cien Saude Colet. 2018 Feb;23(2):471-480. doi: 10.1590/1413-81232018232.15672015.
The objective was to examine the association between life events post diagnosis of breast câncer and metastasis. Cross-sectional study with 300 women attending a reference hospital in oncology in the Espírito Santo. Was used the instrument Life Events Units-LEU/VAS to evaluate life events reported by women. Data were analyzed by using the nonparametric Wilcoxon and chi-square tests. It was performed odds ratio calculation for the variables associated with metastasis. It was found that 21% of the sample reported at least one life event post diagnosis. Of the 46 women who developed metastases, 20 reported one or more life events (p = 0.001). The odds ratio calculated shows that having life events post diagnosis increases by 2.59 (1,37 - 4,91; p = 0,003) times the chance of developing metastasis. When considering the time between diagnosis and the onset of metastasis there was a median of 18.0 months. The study shows a relationship between life events and metastasis, however emphasize the importance of a more complex analysis to better understand the impacts of these events on the onset and progression of breast cancer.
目的是研究乳腺癌诊断后生活事件与转移之间的关联。对圣埃斯皮里图州一家肿瘤学参考医院的300名女性进行横断面研究。使用生活事件单位-LEU/VAS工具评估女性报告的生活事件。通过非参数威尔科克森检验和卡方检验分析数据。对与转移相关的变量进行比值比计算。发现21%的样本报告在诊断后至少发生了一次生活事件。在发生转移的46名女性中，20名报告了一次或多次生活事件（p = 0.001）。计算出的比值比表明，诊断后发生生活事件会使发生转移的几率增加2.59（1.37 - 4.91；p = 0.003）倍。当考虑诊断与转移发生之间的时间时，中位数为18.0个月。该研究表明生活事件与转移之间存在关联，然而强调了进行更复杂分析以更好理解这些事件对乳腺癌发生和进展影响的重要性。
