Division of Gastroenterology, Hepatology, and Nutrition, Center for Nutrition, Vanderbilt University Medical Center, 1211 21st Avenue South, Suite 514, Nashville, TN 37232, USA.
Division of Gastroenterology, Hepatology, and Nutrition, Center for Nutrition, Vanderbilt University Medical Center, 1211 21st Avenue South, Suite 514, Nashville, TN 37232, USA.
Gastroenterol Clin North Am. 2018 Mar;47(1):139-154. doi: 10.1016/j.gtc.2017.09.006. Epub 2017 Dec 7.
Celiac disease is an autoimmune disorder due to the inflammatory response to gluten in genetically predisposed individuals. It causes an enteropathy associated with several nutritional complications. Strict compliance to a gluten-free diet (GFD) is the current primary therapy. Nonceliac gluten sensitivity (NCGS) is a condition in which gluten ingestion leads to systemic symptoms but is not associated with small bowel atrophy or abnormal celiac serologies. A GFD heals celiac disease enteropathy and improves symptoms in NCGS. However, a long-term GFD can be associated with nutritional deficiencies and requires monitoring and guidance.
乳糜泻是一种自身免疫性疾病，由于遗传易感性个体对麸质的炎症反应引起。它会导致与多种营养并发症相关的肠病。严格遵守无麸质饮食（GFD）是目前的主要治疗方法。非乳糜泻麸质敏感（NCGS）是一种麸质摄入会导致全身症状但与小肠萎缩或异常乳糜泻血清学无关的疾病。GFD 可治愈乳糜泻肠病并改善 NCGS 症状。然而，长期 GFD 可能与营养缺乏有关，需要监测和指导。
