Calhoun Benjamin C
Department of Pathology and Laboratory Medicine, University of North Carolina, Women's and Children's Hospitals, 3rd Floor, Room 30212, 101 Manning Drive, Chapel Hill, NC 27514, USA.
Surg Pathol Clin. 2018 Mar;11(1):1-16. doi: 10.1016/j.path.2017.09.001. Epub 2017 Dec 6.
Benign and atypical lesions associated with breast cancer risk are often encountered in core needle biopsies (CNBs) of the breast. For these lesions, the rate of "upgrade" to carcinoma in excision specimens varies widely in the literature. Many CNB studies are limited by a lack of radiological-pathological correlation, consistent criteria for excision, and clinical follow-up for patients who forego excision. This article highlights contemporary diagnostic criteria and outcome data that would support an evidence-based approach to the management of these nonmalignant lesions of the breast diagnosed on CNB.
与乳腺癌风险相关的良性和非典型病变在乳腺粗针活检（CNB）中经常遇到。对于这些病变，在文献中，切除标本中“升级”为癌的发生率差异很大。许多CNB研究受到以下因素的限制：缺乏放射学与病理学的相关性、一致的切除标准以及对放弃切除的患者缺乏临床随访。本文重点介绍了当代诊断标准和结果数据，这些数据将支持对CNB诊断出的这些乳腺非恶性病变进行循证管理。
