Harrison Beth T, Dillon Deborah A
Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Amory 3, Boston, MA 02115, USA.
Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Amory 3, Boston, MA 02115, USA.
Surg Pathol Clin. 2018 Mar;11(1):61-90. doi: 10.1016/j.path.2017.09.002. Epub 2017 Dec 6.
Mucinous lesions of the breast include a variety of benign and malignant epithelial processes that display intracytoplasmic or extracellular mucin, including mucocelelike lesions, mucinous carcinoma, solid papillary carcinoma, and other rare subtypes of mucin-producing carcinoma. The most important diagnostic challenge is the finding of free-floating or stromal mucin accumulations for which the significance depends on the clinical, radiologic, and pathologic context. This article emphasizes the differential diagnosis between mucocelelike lesions and mucinous carcinoma, with a brief consideration of potential mimics, such as biphasic and mesenchymal lesions with myxoid stroma ("stromal mucin") and foreign material.
乳腺黏液性病变包括多种良性和恶性上皮性病变，这些病变表现为胞质内或细胞外黏液，包括黏液囊肿样病变、黏液癌、实性乳头状癌以及其他罕见的黏液产生癌亚型。最重要的诊断挑战是发现游离或间质黏液积聚，其意义取决于临床、放射学和病理学背景。本文重点强调黏液囊肿样病变与黏液癌之间的鉴别诊断，并简要考虑潜在的类似病变，如具有黏液样间质（“间质黏液”）的双相性和间质性病变以及异物。
