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趋磁水生螺菌产生异羟肟酸。

Hydroxamate production by Aquaspirillum magnetotacticum.

作者信息

Paoletti L C, Blakemore R P

出版信息

J Bacteriol. 1986 Jul;167(1):73-6. doi: 10.1128/jb.167.1.73-76.1986.

DOI:10.1128/jb.167.1.73-76.1986
PMID:2941414
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC212842/
Abstract

Spent culture fluids from Aquaspirillum magnetotacticum MS-1 grown at high (20 microM) but not low (5 microM) iron concentration contained material yielding a positive hydroxamate test. Cells possessed six major outer membrane proteins. Three outer membrane proteins ranging from 72,000 to 85,000 daltons were coordinately produced at iron concentrations conducive to hydroxamate production. A 55,000-dalton iron-repressible outer membrane protein was also present in strain MS-1 cultured at low but not high ferric quinate concentration. Culture fluids from strain MS-1 which were hydroxamate positive augmented growth of a Salmonella typhimurium siderophore-deficient (enb-7) mutant in low-iron medium, suggesting a role of hydroxamate in uptake of iron by the cell.

摘要

在高铁浓度(20微摩尔)而非低铁浓度(5微摩尔)下培养的趋磁水生螺菌MS-1的用过的培养液中含有能产生阳性异羟肟酸试验结果的物质。细胞拥有六种主要的外膜蛋白。在有利于异羟肟酸产生的铁浓度下,三种分子量在72,000至85,000道尔顿之间的外膜蛋白协同产生。在低浓度而非高浓度奎尼酸铁培养的MS-1菌株中也存在一种55,000道尔顿的铁抑制性外膜蛋白。来自MS-1菌株的异羟肟酸呈阳性的培养液在低铁培养基中促进了鼠伤寒沙门氏菌铁载体缺陷型(enb-7)突变体的生长,这表明异羟肟酸在细胞摄取铁的过程中发挥了作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e127/212842/70665fb5ed9e/jbacter00206-0084-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e127/212842/0173df8a7900/jbacter00206-0084-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e127/212842/70665fb5ed9e/jbacter00206-0084-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e127/212842/0173df8a7900/jbacter00206-0084-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e127/212842/70665fb5ed9e/jbacter00206-0084-b.jpg

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